sub·for·ni·cal or·gan (SFO),

the intercolumnar tubercle. One of the circumventricular organs., SFO has fenestrated capillaries and is outside the blood-brain barrier. It is thought to be a chemoreceptor zone involved in cardiovascular regulation.

Synonym(s): organum subfornicale [TA]

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References in periodicals archive

Mogenson, "Effects of plasma angiotensin II and hypernatremia on subfornical organ neurons," The American Journal of Physiology, vol.

Long-Term High Salt Intake Involves Reduced SK Currents and Increased Excitability of PVN Neurons with Projections to the Rostral Ventrolateral Medulla in Rats

The thirst-regulating circuit is located in a region of the brain called the subfornical organ (SFO).

Brain Circuit that Regulates Thirst Identified

Thus, circulating AngII may activate neurons at the subfornical organ (67), which sends axonal projections to the SON, increasing MNC activity via AngII release and activation of postsynaptic AngII receptors type-1 (AT1).

Effects of nitric oxide on magnocellular neurons of the supraoptic nucleus involve multiple mechanisms

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