Specific disruption of a
schwann cell dystrophin-related protein complex in a demyelinating neuropathy.
The team boosted
Schwann cell's nutrition-dispensing capability by injecting a protein gene that promotes nerve growth.
A notable feature of the detached nerve terminals described in this paper is that they are distinguishable from
Schwann cells so that they can be patch clamped.
Once the gene that suppresses
Schwann cell growth is "mapped" or located, scientists can begin to develop gene therapy to control the overproduction of these cells in individuals with acoustic neurinoma.
Therefore, BMSCs would be more ready to proliferate and differentiate into other kinds of cells, such as osteoblasts, chondrocytes, vascular endothelial cells, and even
Schwann cells, under the induction condition [56-58].
In this study, the effect of Wnt5a on
Schwann cells was investigated by Wnt5a silencing in RSC96 cells.
On day 7, 21, 28, and 31, vacuolization, degeneration in mitochondria, endoplasmic reticulum and
Schwann cells, neurofilaments, and lack of organelles in the axoplasm occurred.
The optic nerve and its sheath are innervated by sympathetic fibers that are myelinated by
Schwann cells these are a potential source.6 Another possible source is the sympathetic fibers supplying the central artery in case of schwannomas located more centrally within the structure.7 There is also speculation that there exist aberrant
Schwann cells that may give rise to tumours but this appears far less likely.
We retrospectively describe our 5-year experience in using confocal laser scanning microscopy (CLSM) to differentiate the morphological features of
Schwann cells at the time of first resection of neurofibromas arising in NF1 patients (study registration number: researchregistry3681).
GFAP was negative, as sometimes can be seen in
Schwann cells and ganglion cells [11].