rose ben·gal

(rōz' ben'găl), [C.I. 45440]

The sodium salt of tetraiodotetra-chlorfluorescein, used as a stain for bacteria, as a stain in the diagnosis of keratitis sicca, and formerly in liver function tests.

Farlex Partner Medical Dictionary © Farlex 2012

rose ben·gal

(rōz' beng'găl)

[C.I. 45440] A fluorescein derivative used as a biologic stain.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

rose bengal

A biological stain that can be applied to the cornea as eye drops to reveal subtle damage to the outer layer (epithelium). A brand name is Minims Rose Bengal.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

rose bengal

An iodine derivative of fluorescein having vital staining properties but unlike fluorescein it is a true histological stain, which binds strongly and selectively to cellular components. The colour of this stain is red. It has the disadvantage of causing some pain in a good percentage of eyes. It stains dead or degenerated epithelial cells but not normal cells and is used to help in the diagnosis of corneal abrasion, keratitis, keratoconjunctivitis sicca, lagophthalmos, etc. See fluorescein; lissamine green.

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References in periodicals archive

Tani iin laboratuvar kriterleri; (1) Destekleyici: Serum orneklerinden Rose Bengal testi ile antikor pozitifligi; (2) Dogrulayici: Klinik orneklerden Brucella spp.'nin izolasyonu ve/veya daha once tedavi almamis bir olguda tek serum orneginde STA ile antikor titresinin >1:160 olmasi ve/veya en az iki hafta ara ile alinan cift serum orneginde Brucella STA titresinin >4 kat artis olmasidir (8).

Prevelance of Brusellosis in Turkish Republic of North Cyprus/Kuzey Kibris Turk Cumhuriyeti'nde Bruselloz Prevalansi

The seropositivity of 9.6% using Rose Bengal Plate Test (RBPT) is higher than that obtained by Ogugua et al., 2014, whose findings revealed an overall seroprevalence of 2.83% of brucellosis among goats screened across four states in Nigeria.

Seroprevalence of Brucellosis and Associated Risk Factors among Indigenous Breeds of Goats in Wukari, Taraba State, Nigeria

Rose Bengal Plate test (RBPT) and indirect Enzyme-Linked Immunosorbent Assay (i-ELISA) test were performed on a total of 1031 head of cattle from 82 herds (18 villages communities) owned by 52 farmers.

Seroprevalence and Associated Risk Factors of Brucellosis among Indigenous Cattle in the Adamawa and North Regions of Cameroon

Serum samples were screened initially by Rose Bengal Plate Test (RBPT) and then confirmed by Serum Agglutination Test (SAT) as described by Alton et al.

Molecular Identification of Bovine Brucellosis Causing Organisms at Selected Private Farms in Pothohar Plateau, Pakistan

RSA antigen was prepared using Rose Bengal dye and compared with a commercially prepared RSA antigen.

PREPARATION OF MYCOPLASMA SYNOVIAE ANTIGENS AND EVALUATION BY RAPID SLIDE AGGLUTINATION AND ENZYME LINKED IMMUNOSORBENT ASSAY

On the other hand, the photochemical properties of various xanthenic dyes, mainly rose bengal (RB) and eosin (Eo), have been extensively studied due to their diverse applications that derive mainly from their large molar absorption coefficients in the visible region and their high quantum yields of singlet oxygen generation.

Photophysical Behavior of Modified Xanthenic Dyes Embedded into Silsesquioxane Hybrid Films: Application in Photooxidation of Organic Molecules

That is the case of cyclic anionic xanthene dyes with three aromatic rings in linear arrangement and an atom of oxygen in the central ring as, for example, Rose Bengal (RB), erythrosin B (EB), eosin Y (EY), and fluorescein (FL) (Figure 1).

Photodynamic Efficiency of Xanthene Dyes and Their Phototoxicity against a Carcinoma Cell Line: A Computational and Experimental Study

PV-10 is an injectable formulation of Rose Bengal that is under investigation as an ablative immunotherapy for solid tumor cancers.

Provectus Biopharmaceuticals partners with POETIC for the study the potential of PV-10 in pediatric cancer

[6] There are numerous commercial kits and serological methods commonly used and recommended, including the Rose Bengal test, serum tube agglutination and enzyme-linked immunosorbent assay (ELISA).

Human brucellosis in South Africa: public health and diagnostic pitfalls

Rose Bengal is a fluorescein derivative, which stains dead and damaged cells and mucus with no effect over epithelial defects or intercellular spaces.

Conjunctival impression cytology in diagnosis of dry eye in presence of normal tear film function

Sera from 110 volunteers were collected and analyzed by employing serology (Rose Bengal Test, competitive ELISA, FPA) and serum PCR assay.

Application of Serum Based PCR and Fluorescence Polarization Assay for Diagnosis of Brucellosis among People Occupationally at Risk to Disease