Grading ocular surface staining--fluorescein used to assess corneal damage, and
lissamine green for assessing conjunctival staining (see Figure 2).
Evaluation of the effect of
lissamine green and rose bengal on human corneal epithelial cells.
The subjects were submitted to the following tests, exactly in the order cited, during the first visit (T0) and at follow-up visits (T1 and T3): best spectacle-corrected visual acuity (BSCVA) converted for LogMar scale, tear film osmolarity by electrical conductivity [16], biomicroscopy [17], Schirmer 1 test without anesthesia [18], tear film breakup time (TBUT) [18], fluorescein staining [19], completing patient's symptoms questionnaire and ocular surface disease index (OSDI) [20],
lissamine green staining [18], and impression cytology (IC) and staining by periodic acid Schiffhematoxylin (PAS-H).
And then Schirmer test, tear film tear break-up time (TBUT), corneal epithelial staining using fluorescein and conjunctival epithelial staining using
lissamine green were performed to detect dry eye.
Secondary outcome measures (3 months after intervention) were the Schirmer's 1 test for tear production, Tear Film Break-up Time (TBUT), and
Lissamine green.
During the study, both concentrations (0.05% and 0.09%) of Seciera, indicated statistical superiority over placebo-vehicle for the co-primary efficacy endpoint of change from baseline at week 12 in total conjunctival
lissamine green staining.
Objective tests comprising blink rate, Schirmer's test, tear film break up time, rose Bengal test, and
Lissamine green staining were carried out.
Bacic, "Photocatalytic degradation of
Lissamine Green B dye by using nanostructured sol-gel Ti[O.sub.2] films," Journal of Alloys and Compounds, vol.
Patients were assessed at baseline, four, 12 and 24-week intervals using a variety of disease parameters including Ocular Surface Disease Index (OSDI) symptom severity questionnaire, topographical indices (SAI and SRI), inflammatory biomarkers (HLA-DR and CD11c), Schirmer tear flow measurement, tear breakup time (TBUT), and conjunctival fluorescein and
lissamine green staining.
The purpose of this study was to determine the association between PEX syndrome and CCh and the influence of PEX on ocular surface parameters, employment of ocular surface disease index (OSDI) scores, tear break-up time testing (BUT),
lissamine green (LG) staining and Schirmer testing.
Using the company's patented disposable electrical sensor technolo gy and a unique sequential methodology, die instrument offers superior analytical performance compared to DPD or
Lissamine Green methods, while reducing the potential for user error.