Susceptibility to over production of cytokines in acute
rheumatic carditis and their role in the pathogenesis.
Diagnosis of ARF was based on the revised Jones criteria, whereas acute rheumatic carditis was defined as the presence of a new murmur, tachycardia, gallop rhythm, cardiomegaly, or congestive heart failure and is diagnosed by echocardiography.
A hundred children with rheumatic carditis (41 male; 59 female) and 100 healthy controls (33 male; 67 female) were recruited.
Furthermore, MVP has often been reported in patients with rheumatic carditis, as a long-term sequela; several studies have found the prevalence to be 14%-45% (24, 25).
In rheumatic carditis, the development of leaflet fusion after the formation of granulation tissue and fibrosis results in valve insufficiency as well as stenosis.
By those findings, HSP vasculitis with acute rheumatic carditis was diagnosed and prednisone 2 mg/kg/day p.o.
Henoch- Schonlein purpura with rheumatic carditis. Indian J Pediatr 2004; 71:371-2.
inflammatory Valvular prolapse produced by Acute
Rheumatic carditis; echocardiographic analysis of 66 cases of Acute
Rheumatic carditis.
Majority of patients with
rheumatic carditis have normal LV systolic function.
Pathophysiologically, repeated
rheumatic carditis can result in subvalvular or valvular thickening before the development of leaflet retraction and thereby regurgitation.
This study shows higher sensitivity and positive predictive value of 2D ECHO in detecting
rheumatic carditis and rheumatic heart disease.
Characteristic changes in cardiac contour and various pulmonary parenchymal manifestations are frequently seen in
rheumatic carditis. These changes usually facilitate the diagnosis of disease.