(7) Several pharmacologic agents including hyoscine butyl bromide (buscopan), glucagon, nitrates, calcium channel blockers, and
papaveretum and nonmedicinal agents such as water, effervescent crystals, papain and fresh pineapple juice have been used in the treatment of esophageal food impaction with variable success rate.
Wheal diameters to four different concentrations of morphine, pethidine and papaveretum were similar in both sensitive and control subjects, clearly demonstrating that skin testing was not of diagnostic value.
In the late 1980s when the reaction occurred, papaveretum contained 47.5 to 52.5% morphine, 2.5 to 5.0% codeine, 16.0 to 20.0% narcotine (noscapine) and 2.5 to 7.0% papaverine (104).