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Papanicolaou test

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Papanicolaou test (smear)

 [pap″ah-nik″o-la´oo]
a simple, painless test used most commonly to detect cancer of the uterus and cervix; it is based on the discovery by Dr. George N. Papanicolaou (1883–1962) that malignant uterine tumors slough off cancerous cells into surrounding vaginal fluid. Called also Pap test and Pap smear.

The Papanicolaou technique, an exfoliative cytological staining procedure, is used also in diagnosis of lung, stomach, and bladder cancers. It can be performed on any body excretion (urine, feces), secretion (sputum, prostatic fluid, vaginal fluid), or tissue scraping (as from the uterus, cervix, or stomach). The sample is removed from the area being examined, placed on a glass slide, stained, and then studied under a microscope for evidence of abnormal or cancerous cells.

In five minutes the Pap test can reveal uterine or cervical cancer at a stage in which it produces no visible symptoms, has done no damage, and usually can be completely cured. It is recommended that all women over age 18, and younger women who have been sexually active, should have an annual Pap test and pelvic examination.
Pap smear. From Lammon et al., 1995.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

Papanicolaou test

(pä′pə-nē′kə-lou′, păp′ə-nĭk′ə-lou′)
n.
The Pap smear.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Papanicolaou,

George N., Greek-U.S. physician, anatomist, and cytologist, 1883-1962.
Papanicolaou examination
Papanicolaou smear - Synonym(s): Pap smear
Papanicolaou smear test - Synonym(s): Pap test
Papanicolaou stain - a multichromatic stain used in cancer screening, especially of gynecologic smears.
Papanicolaou test - Synonym(s): Pap test
Pap smear - vaginal or cervical cells obtained for cytological study. Synonym(s): Papanicolaou smear
Pap test - examination of cells stained with Papanicolaou stain. Synonym(s): Papanicolaou smear test; Papanicolaou test
Medical Eponyms © Farlex 2012
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References in periodicals archive
Our findings highlight individual (STI knowledge, sexual practices), social/structural (GNC stigma) and health care (past twoyear Papanicolaou test, having a regular source of health care, HCP knowledge and comfort with one's sexual orientation) factors associated with past two-year CBE among LGBQ women.
Approximately 14.9% of married women reported having had a Papanicolaou test in the preceding 3 years in Jordan, compared with 86.0% of women aged [greater than or equal to] 18 years in the United States; 9.3% of women aged [greater than or euqual to] 40 years reported having had a mammogram in the preceding 2 years, compared with 74.9% of U.S.
Cytologic features of low-grade squamous intraepithelial lesion in ThinPrep Papanicolaou test slides and conventional smears: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology.
The survey provides prevalence estimates for the use of screening measures, such as blood cholesterol level, blood stool test, sigmoidoscopy, Papanicolaou test, mammography, and influenza and pneumococcal vaccinations.
Currently, 4 HPV testing platforms are approved by the FDA for triage of a Papanicolaou test diagnosis of atypical squamous cells of undetermined significance (reflex testing) and as an adjunct to the Papanicolaou test (cotesting) in women 30 years and older: HC2 was approved for these purposes in 2003, Cervista in 2009, and Aptima and cobas in 2011 (cobas was further approved for primary HPV screening of women 25 years and older in 2014).
In order to practice Papanicolaou test examination and comply with CLIA, cytopathologists and cytotechnologists are required to pass one national gynecologic cytology proficiency examination annually.
Specimen Adequacy for the Liquid-Based Cervical Cytology and Conventional Papanicolaou Test Groups, Total and Stratified by Visit Type
The Papanicolaou test for cervical cancer detection: a triumph and a tragedy.
Human papillomavirus typing and viral gene expression analysis for the triage of women with abnormal results from Papanicolaou test smears to colposcopy.
The greatest perceived need was for laboratory training related to the Papanicolaou test.
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