major

ma·jor

(mā'jŏr), This form of the adjective is used with masculine nouns (sulcus major, plural sulci majores) and feminine nouns (pelvis major, plural pelves majores). With neuter nouns the form majus is used (omentum majus, plural omenta majora).

Larger or greater in size of two similar structures.

[L. comparative of magnus, great]

Farlex Partner Medical Dictionary © Farlex 2012

transfusion guidelines

Transfusion medicine Guidlelines for use of blood components, which are usually written in a hospital's policy manual. See Transfusion criteria, Transfusion medicine.

Transfusion guidelines, general criteria

Hemoglobin

 < 8g/dL if healthy and stable

 < 11g/dL if Pt is at risk of ischemia

Acute blood loss ≥ 15% (est) blood volume, tachycardia, oliguria

Symptomatic anemia resulting in tachycardia, change in mental status, cardiac ischemia, or SOB Transfusion 1996; 36:144. See Transfusion guidelines.

Packed RBCs  

•  Hemorrhage

•  Active Physiologic instability, including tachycardia, ↓ in systolic BP > 30 mm Hg below baseline, orthostatic hypotension, angina, mental confusion, agitation

•  Chronic Physiologic instability–see above, refractory state.

•  Sickle cell anemia

Refractory crisis, acute lung syndrome, CVA, priapism, hepatic infarct, acute papillary necrosis, general anesthesia, contrast studies

Platelets  

• Platelet count < 30,000/µL

•  Functional platelet deficit

•  Surgical prophylaxis

•  Massive bleeding

Cryoprecipitate  

•  Active bleeding, fibrinogen < 100 mg/dL

•  Massive bleeding

•  DIC w/ bleeding

•  1⁰ fibrinolysis

Dysfibrinogenemia

Major ↓ in fibrinogen, factor VIII, von Willebrand factor

± in reversible liver disease

Queens Hospital Medical Center, 1990

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Patient discussion about major

Q. Major mood disorder! Hi guys! My topic is all about major mood disorder, bipolar 1 mixed with psychotic features and I would like to ask if I could get some information regarding with its introduction on international, national and local. Hope you all understood what I mean to ask.

A. Methinks all these brain disorders have everything to do with a lack of copper. With all our modern technology and artificial fertilizers and processing of foods, the food has become so depleted of minerals that our bodies and brains have become so depleted that we cannot even function properly. Start taking kelp, calcium magnesium, cod liver oil, flax seed oil, and raw apple cider vinegar. This will bring healing and normal function to the brain and body systems. The emotions will calm down and be more manageable. If you are taking a vitamin with more manganese than copper it will add to the dysfunction. Don't waste your money. There you are! Some solutions rather than more rhetoric about the problem.

Q. I heard that the major risk in diarrhea is dehydration, why is that? How can I avoid that? Are there other dehydration causes I should beware of?

A. vomiting will also dehydrate you about as dangerously as diarrhea fye

Q. Why do I have major headaches during flight landings? I always get really strong headaches just before landing. Lately, they have been so severe that I honestly feel like my head is going to explode. The closer the plane gets to the ground, the more pain I have. After landing, the pain eases a little but I have a headache at least a day or two afterwards. Do anyone have any suggestions?

A. The air pressure change makes air expand and if your ear canal is blocked –there is a severe pressure on your inner ear/estacian tube. This is painful.
You might try swallowing real hard or yawning, or “popping” your ears. This is called "Valsalva" maneuver :
http://en.wikipedia.org/wiki/Valsalva_maneuver

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