Just like in adults, the symptoms of a major depressive episode associated with
bipolar I disorder, or with major depressive disorder (MDD), are identical.
The distinguishing feature between those with
Bipolar I Disorder who had a job and those who did not was the availability of help with everyday chores.
Hasin and colleagues (1989) found that patients with bipolar II disorder were likely to have an earlier remission from alcoholism compared with patients with schizoaffective disorder or
bipolar I disorder. Researchers have also proposed that the presence of mania may precipitate or exacerbate alcoholism (Hasin et al.
Predominant recurrence polarity among 928 adult international
bipolar I disorder patients.
(7) Notably, the kappa statistic for inter-rater agreement was good for bipolar II disorder ([kappa]=0.40), which was greater than that for MDD ([kappa]=0.28) but lower than that for
bipolar I disorder ([kappa]=0.56).
In the United States (US), the estimated lifetime prevalence of bipolar disorder is 2% to 4%, with about 1 % of US adults having a lifetime history of
bipolar I disorder. (1,2) It has been estimated that in 2009, the direct and indirect costs associated with bipolar disorder amounted to at least $151 billion in the US.
More than 90% of individuals who have a first manic episode have future episodes, and patients with
bipolar I disorder generally have more episodes, both depressive and manic, over their lifetime than do patients with recurrent major depressive disorder.
Posttraumatic stress disorder can worsen outcomes in people with
bipolar I disorder, as measured by a lower likelihood of recovery, greater proportion of rapid cycling periods, increased risk of suicide attempts, and worse quality of life.
(20) The lifetime risk of anxiety disorders in
bipolar I disorder has been reported to be 93% compared with 58% in unipolar depression.
The longterm natural history of the weekly symptomatic status of
bipolar I disorder. Arch Gen Psychiatry.
Therefore, Sandra Dittman, Ph.D., and her colleagues at Ludwig-Maximilians-Universitat Munich evaluated 65 patients with
bipolar I disorder, 38 with bipolar II disorder, and 62 healthy controls using the Structured Clinical Interview for DSM-IV and a other tools (Bipolar Disord.
The manias of
bipolar I disorder are much more readily distinguishable from the mood instability or reactivity of BPD.