Fixed monocytes (
Kupffer cells) were present in the lining of sinusoids (Fig.1).
Microscopically, hepatocytes were showed minimal degeneration, sinusoidal congestion and moderate multifocal aggregations of golden yellow coloured pigment in
kupffer cells (Fig.
Besides DCs, intrahepatic
Kupffer cells also participate in the anti-HBV immune response, partly through interfering with the NK cells.
Histoplasmosis features portal lymphohistiocytic inflammation and sinusoidal
Kupffer cell hyperplasia, and organisms are generally present within both portal macrophages and
Kupffer cells (Figure 8, A and B).35 Discrete granulomas and giant cells are seen in only a minority of cases.
Examples include
Kupffer cells, macrophages residing in the liver, and microglia, residing in the central nervous system.
These changes were accompanied by swelling of
Kupffer cells in congested sinusoidal ves-sels.16 The determination of transaminase activity in serum is a common means of detecting liver damage.
(2007) reported that a high-fat diet induced PS externalization on erythrocytes and erythrophagocytosis by
Kupffer cells in the liver, resulting in inflammation and hepatic fibrosis.