Har·dy-Wein·berg e·qui·lib·ri·um

(har'dē wīn'bĕrg),

that state in which the genetic structure of the population conforms to the prediction of the Hardy-Weinberg law; it is not a stable equilibrium, although for a large mating population it may be approximated.

Synonym(s): random mating equilibrium

Farlex Partner Medical Dictionary © Farlex 2012

Hardy,

Godfrey H., English mathematician, 1877-1947.

Hardy-Weinberg equilibrium - the state in which the genetic structure of the population conforms to the prediction of the Hardy-Weinberg law. Synonym(s): random mating equilibrium

Hardy-Weinberg law - if mating occurs at random with respect to any one autosomal locus in a population in which the gene frequencies are equal in the two sexes, and the factors tending to change gene frequencies are absent or negligible, then in one generation the probabilities of all possible genotypes will on average equal the same proportions as if the genes were assembled at random.

Weinberg,

Wilhelm, German physician, 1862-1937.

Hardy-Weinberg equilibrium - see under Hardy, Godfrey H

Hardy-Weinberg law - see under Hardy, Godfrey H

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References in periodicals archive

GENEPOP 4.2 (Raymond and Rousset, 1995) was employed to estimate Potential deviation from Hardy-Weinberg equilibrium (HWE).

GENETIC DIVERSITY OF THE CAPTIVE CHINESE POND TURTLE (MAUREMYS REEVESII) POPULATIONS IN CHINA ASSESSED BY MICROSATELLITE MARKERS

The genotype distribution for each polymorphism was evaluated for Hardy-Weinberg equilibrium. The strength of the association between MTHFR gene polymorphisms and CHD was evaluated using the I2 test and odds ratios (OR) with 95% confidence intervals (CI).

Interaction between MTHFR Polymorphisms and Maternal Age Increases the Risk of Congenital Heart Defects in Down Syndrome

A I2 test was used to compare the allele frequency and genotype distribution of each variant following Hardy-Weinberg equilibrium. Unpaired t-test was used to compare between two physical parameters.

Genetic variants of calcium sensing receptor gene and risk of colorectal cancer: A case-control study

If sub-populations are bred as closed flocks in isolation from each other, as is the case in the present study, a deviation from Hardy-Weinberg equilibrium is an expected consequence.

Genetic characterization and population structure of six brown layer pure lines using microsatellite markers

Number of alleles (Na), effective number of alleles (Ne), observed heterozygosity (Ho), expected heterozygosity (He), and the Hardy-Weinberg equilibrium test (HW) were calculated for each locus by the GenAlex software version 6.5 (PEAKALL & SMoUSE, 2012).

Transferability of heterologous microsatellite primers in Brycon gouldingi/Transferibilidade de primers microssatelites heterologos em Brycon gouldingi

Statistical analysis: Hardy-Weinberg equilibrium analyses were performed using Hardy-Weinberg equilibrium calculator in www.oege.org/software/Hardy-Weinberg (22).

Association of Growth Factors Genes with Miscarriage

Although for many years the importance of using specific STR for human identification, forensic DNA casework, missing persons, mass disasters, monitoring needle sharing, monitoring transplants, military casualties and so on has been accepted, for detection of their impact for each population, their forensic parameters specially Hardy-Weinberg equilibrium should be calculated (4).

Pattern Analysis of Short Tandem Repeats Allele Frequencies among the Population of Khuzestan Province, South of Iran

Both authors suggested that these alleles could explain the deviations from the Hardy-Weinberg equilibrium at the loci where they are present.

NOVEL MICROSATELLITE MARKERS FOR THE INVASIVE GOLDEN MUSSEL LIMNOPERNA FORTUNEI

Chi-square test was used to check for deviation of genotype distribution from the Hardy-Weinberg equilibrium in both groups.

The C-565T Polymorphism (rs2422493) of the ATP-binding Cassette Transporter A1 Gene Contributes to the Development and Severity of Coronary Artery Disease in an Iranian Population

Hardy-Weinberg equilibrium was tested using the chi-square test as well.

Association of methylenetetrahydrofolate reductase gene 677C>T polymorphism with post-stroke depression risk and antidepressant treatment response in Han Chinese