It is thought to arise from Fordyce granules or salivary gland elements [5].
It may arise from intraoral minor salivary glands, parotid duct, or Fordyce granules [4, 5].
The most prevailing lesions encountered in present study were fordyce granules and were more frequently seen on the buccal mucosa and vermillion border of lip with higher male predilection and this finding is consistent with several other studies.9,10,11,12 Linea alba was the 2nd most common oral soft tissue lesion in present study which collaborates with the research of Mohammad Ali conducted in Kuwait.
Present study findings showed increased percentage of fordyce granules in 30-40 years-and least number of cases were found in 10-20 years of age group.
Fordyce granules were found to have a high prevalence among patients of this study.
The presence of recognizable Fordyce granules (intraoral ectopic sebaceous glands) may be associated with systemic diseases, and a previously unrecognized activation of the sebaceous gland system may occur in individuals carrying hereditary nonpolyposis colorectal cancer syndrome, or Lynch syndrome, according to a controlled study of genetically unrelated patients.
Following examination of the subjects' oral mucosa surfaces, they were categorized as either Fordyce granule (FG) positive or FG negative.
Fordyce granules are referred to as benign sebaceous glands, which are ectopic in distribution and are characterized by the multiple light yellow raise papules, occurring mainly in the lip region, buccal mucosa,vermillion border,and retromolar region.11 In this study, 61% fordyce's granules were found on buccal mucosa followed by 20 % on upper lip, 10% on retromolar area, 6% on lower lip, 1.5% on vermilion border and 0.76% on gingiva.
Fordyce granules on the prolabial and oral mucous membranes of a selected population.