Cosmegen
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Cosmegen
[kos´mĕ-jen] trademark for a preparation of
dactinomycin, an
antitumor antibiotic.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Cosmegen
(kŏs′mə-jən) A trademark for the drug dactinomycin.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Actinomycin D
A relatively toxic antibiotic produced by Streptomyces spp, which is used as a chemotherapeutic.
Mechanism Inhibits DNA transcription by RNA polymerase.
Indications Rhabdomyosarcoma, Wilms’ tumour, gestational trophoblastic tumour
Adverse effects Anorexia, nausea, vomiting, myelosuppression with pancytopenia, diarrhoeaSegen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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