Churg-Strauss syndrome

[cherg strous]

a form of systemic necrotizing vasculitis in which there is prominent lung involvement with severe asthma, eosinophilia, and granulomatous reactions. If present, skin lesions consist of tender subcutaneous nodules and bruiselike spots. Called also allergic granulomatosis, allergic granulomatous angiitis, and Churg-Strauss vasculitis.

Churg-·Strauss syn·drome

(chŭrg strows),

asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas.

Synonym(s): allergic granulomatosis, allergic granulomatous angiitis

Farlex Partner Medical Dictionary © Farlex 2012

Churg-Strauss syndrome

An autoimmune vasculitis of small to medium blood vessels with hypereosinophilia arising in a background of asthma and allergic rhinitis, which may be accompanied by tissue eosinophilia, peripheral neuropathy, gastrointestinal necrosis, cardiac lesions, and renal disease. Skin lesions are common in the form of purpura, erythema, urticaria and nodules arising on the scalp and/or extremities.

Churg-Strauss syndrome

Allergic granulomatosus & angiitis Internal medicine A small vessel vasculitis characterized by eosinophil-rich and granulomatous inflammation of the respiratory tract, formation of ANCA and necrotizing vasculitis of small-to-medium-sized vessels associated with asthma, edema. See Small vessel vasculitis, Systemic vasculitis.

Churg-Strauss syndrome

A rare form of blood vessel inflammation (vasculitis) that is almost invariably accompanied by severe ASTHMA. The cause is unknown and although the condition responds well to treatment with steroids or immunosuppressive drugs, the asthma usually persists. The syndrome is distinct from other vasculitides. There are suspicions that it may possibly be caused by certain drugs used to treat asthma, especially antileukotriene drugs.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Churg,

Jacob, Polish-born U.S. pathologist, 1910–.

Churg-Strauss syndrome - asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas. Synonym(s): allergic granulomatosis; allergic granulomatous angiitis; Strauss-Churg-Zak syndrome

Strauss,

Lotte, U.S. pathologist, 1913-1985.

Churg-Strauss syndrome - see under Churg

Strauss-Churg-Zak syndrome - Synonym(s): Churg-Strauss syndrome

Zak,

Frederick G., U.S. physician.

Strauss-Churg-Zak syndrome - Synonym(s): Churg-Strauss syndrome

Medical Eponyms © Farlex 2012

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References in periodicals archive

Kobayashi et al., "Churg-strauss syndrome versus chronic eosinophilic pneumonia on high-resolution computed tomographic findings," Journal of Computer Assisted Tomography, vol.

Systemic granulomatous diseases associated with multiple palpable masses that may involve the breast: case presentation and an approach to the differential diagnosis

Churg-Strauss syndrome associated with acalculous cholecystitis and liver involvement.

Eosinophilic Granulomatosis with Polyangiitis Manifested by Cholecystitis and Mononeuritis Multiplex: A Case Report

Faure et al., "Hepatitis C virus infection with and without cryoglobulinemia as a case of Churg-Strauss syndrome," Journal of Rheumatology, vol.

A Rare Case of Eosinophilic Granulomatosis with Polyangiitis Associated with Cryoglobulinemia Presenting with a Bullous Skin Eruption of the Lower Limbs

Wang et al., "Acase report of Churg-Strauss syndrome presenting with cardiogenic shocktreated with extracorporeal membrane oxygenation," Medicine, vol.

Cardiogenic Shock: An Unusual Initial Presentation of Churg-Strauss Syndrome

Neurolaryngeal involvement in Churg-Strauss syndrome. Eur Arch Otorhinolaryngol.

Paralisis unilateral de cuerda vocal como manifestacion inicial de poliangitis microscopica grave

Toumelin et al., "Long-term followup of polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: analysis of four prospective trials including 278 patients," Arthritis and Rheumatism, vol.

Spontaneous Retroperitoneal Haematoma due to Polyarteritis Nodosa: Report of a Case and Literature Review

When his loving wife Ethel, who he refers to as Effie, was diagnosed with Churg-Strauss syndrome, an autoimmune condition that causes the inflammation of small and medium-sized blood vessels in persons with a history of airway allergic hypersensitivity, Alan thought it would be best for them both to move to Bahrain to be near their daughter Linda, 57, an executive assistant to the co-chief executive officer and chief financial officer of Investcorp, and granddaughters.

Trials and tribulations

Subsets include eosinophilic gastrointestinal disorders (affects esophagus, stomach, or intestines); eosinophilic granulomatosis with polyangiitis, aka Churg-Strauss Syndrome, (affects lungs, sinuses, heart, and various organ systems); and hypereosinophilic syndrome (affects blood and organs).

American Partnership for Eosinophilic Disorders Celebrates National Eosinophil Awareness Week

Patients with allergic disorders, pemphigus, parasite infestations, Castleman's disease, Churg-Strauss syndrome, or IgG4-RD were excluded.

Elevated serum IgG4 defines specific clinical phenotype of rheumatoid arthritis