Medical

4-hydroxyproline oxidase

4-·hy·drox·y·pro·line ox·i·dase

1. a flavoenzyme that catalyzes the conversion of 4-hydroxyproline to Δ'-pyrroline-3-hydroxy-5-carboxylate using FAD; this enzyme appears to be deficient in people with hyperhydroxyprolinemia;

2. an enzyme that catalyzes the reaction of 4-hydroxyproline with NAD⁺ to form NADH and 4-oxoproline.

Synonym(s): 4-oxoproline reductase

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