(ziks'in), [MIM*602002]
A cytoplasmic protein found in a number of distinct types of adherens junctions; it may play a role in the organization of membrane-cytoskeletal attachments.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
A recent publication revealed that Zyxin, a scaffold protein encoded by ZYX, was required in TGF-[beta] signaling pathway in response to hypoxia [77].
Song, "Association of resistance to avian coccidiosis with single nucleotide polymorphisms in the zyxin gene," Poultry Science, vol.
Index Gene selection Description 1834 M23197 CD33 antigen (differentiation antigen) [22] 1882 M27891 CST3 cystatin C [22] 3847 U82759 GB DEF = homeodomain protein HoxA9 mRNA [23] 4847 X95735 Zyxin [23] 6041 L09209 APLP2 [22] Note.
Live Cell Imaging and Image Processing for Observation of Actin and Zyxin. Swiss 3T3 fibroblasts expressing pAcGFP1-actin and pTagRFP-zyxin plated on the silicone substrate embedded with fluorescent dark red microspheres (Figure 1(a)) were observed at 37[degrees]C 5% C[O.sub.2] using laser scanning confocal microscopy (A1R; Nikon) with a Plan Apo 60x oil immersion objective (NA 1.40; Nikon).
As a component of focal adhesions, Testin interacts with the cytoskeletal protein such as zyxin, talin, vasodilator-stimulated phosphoprotein, Mena, extractable nucler antigen (EVL), alphall-spectrin, actin and actin-related proteins 7A.
Zyxin binds alpha-actinin and the CRP protein and helps cell adhesion [24] and the cells used in this study expressed Zyxin.
For example, the team found that in a 3-D environment, cells possessing the protein zyxin would move in a random way, exploring their local environment.
On the one hand, mitochondria are crucial for cell motility via their interaction, mediated by the outer membrane protein zyxin, with the actin cytoskeleton.
For EIA, we used the physiologic VASP binding partner zyxin as a capture molecule.
"Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis," Journal of Andrology 25(2): 200-215.
Ajuba is novel group 3 LIM protein along with zyxin, paxillin, trip6 and others.