One study analyzed paw elevation time (PET) and Von Frey test in groups of rats submitted to ACLT or zymosan
induction, with subsequent use of SrRan at doses of 30 and 300 mg x [kg.sup.-1] x [day.sup.-1].
In addition, maresin 2 showed the potential anti-inflammatory action in mouse peritonitis initiated by intraperitoneal injection of zymosan
. This study found that maresin 2 is equivalent to maresin 1 in limiting neutrophil infiltration, whereas maresin 1 is more effective in enhancing macrophage phagocytosis than maresin 2 .
Fernandez, "The induction of IL-10 by zymosan
in dendritic cells depends on CREB activation by the coactivators CREB-binding protein and TORC2 and autocrine PGE2," The Journal of Immunology, vol.
Two novel Toll genes (EsToll1 and EsToll2) from Eriocheir sinensis are differentially induced by lipopolysaccharide, peptidoglycan and zymosan
. Fish Shellfish Immunol., 35(4): 1282-1292.
Inaba, "Efficient capture of Candida albicans and zymosan
by SIGNR1 augments TLR2-dependent TNF-a production," International Immunology, vol.
In addition, other "danger signals" such as bacterial or fungal endotoxins (e.g., lipopolysaccharide [LPS] or zymosan
A), tissue injury markers (e.g., uric acid, hyaluronic acid), immune activation (e.g., CD40L, inflammatory cytokines), and even angiotensin II cause potent activation/maturation of DC [2,3].
Wang et al., "Preparation of rat model of systemic inflammatory response syndrome induced by zymosan
," Zhejiang Da Xue Xue Bao Yi Xue Ban, vol.
In a study on rainbow trout Roher and his co-workers (2011) showed that LPS and zymosan
are major inducers of TNF-a secretion, although this secretion is not initially associated with the induction of mRNA expression of TNF-a.
Completely different results were obtained for the same species of molluscs after injection of zymosan
(La Peyre et al.
(10 mg/mL, Sigma) was mixed with the serum of adult rockfish, which were not used in this feeding experiment, and incubated at 25[degrees]C for 30 min.
A NBT solution of 0.28% in normal saline and a zymosan
(yeast) solution of 1% in normal saline was used.