Cldn5: claudin-5, COX: cyclooxygenase, CRP: C-reactive protein, Fcy receptor: fragment crystallizable region, ICAM1: intracellular adhesion molecule-1, IL: interleukin, NADPHox: nicotinamide adenine dinucleotide phosphate oxidase, NF[kappa]B: nuclear factor kappa-light-chain-enhancer, MMP: matrix metalloproteinase, MLC: myosin light chain, MLCK: myosin light chain kinase, PGE: prostaglandin, PKC: protein kinase C, sICAM: soluble ICAM, sTNF-[alpha]R: soluble TNF-[alpha] receptor, VEGF: vascular endothelial growth factor, TNF: tumor necrosis factor, and ZO: zonula
Pathological interactions of bacteria and toxins with the gastrointestinal epithelial tight junctions and/or the zonula
adherens: an update.
Different molecules have been identified as the components of TJ such as transmembrane protein claudins, occludin, and peripheral membrane protein zonula
Bacillus subtilis protects porcine intestinal barrier from deoxynivalenol via improved zonula
Gotteland, "Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula
occludens-1 expression," Journal of Agricultural and Food Chemistry, vol.
Binding these proteins enables the formation of complexes that are, in turn, connected with actin filaments (in the case of zonula
adherens junctions) or with keratin filaments (in the case of macula adherens junctions).
Accordingly, the present study was designed to explore effect of Tan IIA on BBB and cerebral edema after experimental stoke, furthermore, we studied Tan's influence on expression of the expression of intercellular adhesion molecule-1 (ICAM-1), matrix metalloproteinase-9 (MMP-9), the degradation of tight junction proteins zonula
occludens-1 (ZO-1) and Occludin to further understand its protective mechanism.
RESULTS: Oral administration of coplanar PCB126, mono-ortho-substituted PCB118, and non-coplanar PCB153 (each at 150 [micro]mol/kg body weight) differentially altered expression of the TJ proteins claudin-5, occludin, and zonula
occludens-1 in brain capillaries.
In addition, the down modulation of expression of members of tight junction proteins such as zonula
occludens (ZO-1), occludin, and P-glycoprotein (P-gp), a transmembrane glycoprotein located on the apical/luminal membrane of brain microvascular endothelial cells (BMVEC) that transports endothelium-penetrating lipophilic molecules back into the blood were found in SCID mouse model of HIVE.
AJs can be organized either as focal spot junctions or as a belt-like zonula
adherens (ZA) in mature epithelia.
Numerous mitochondria were observed in the apical cytoplasm, and were connected to the neighboring ceils with zonula
adherens at the apico-lateral cell membrane (Fig.
En 1979 Campbell presento la teoria sobre el mecanismo del GP, incluyendo la concavidad posterior del iris y su contacto con la zonula