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A drug that inhibits leukotriene formation, used to treat asthma.
A64077An experimental therapeutic which inhibits the 5-lipoxygenase pathway of arachidonic acid metabolism, which attenuates the bronchoconstriction response in asthmatics to cold air and allergen-induced nasal constriction, a response attributed to the eicosanoids produced by 5-lipoxygenase—e.g., sulfidopeptide leukotrienes, 5-HETE, and leukotriene B4.
zileutonZyflo® Clinical medicine An inhibitor of 5-lipoxygenase, an enzyme central to leukotriene synthesis, which mediates inflammatory responses Indications Asthma. See Asthma.
A medication that interferes with the biosynthetic pathway that produces leukotrienes; used to help prevent asthma attacks.
Mentioned in: Leukotriene Inhibitors