yohimbine


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yo·him·bine

(yō-him'bēn),
An alkaloid, the active principle of yohimbé, the bark of Corynanthe yohimbi (family Rubiaceae); it produces a competitive blockade, of limited duration, of adrenergic α-receptors; has also been used for its alleged aphrodisiac properties.

yohimbine

/yo·him·bine/ (yo-him´bēn) an alkaloid chemically similar to reserpine, from the bark of the yohimbe tree; it possesses alpha-adrenergic blocking properties and is used as the hydrochloride as a sympatholytic and mydriatic, and for the treatment of impotence.

yohimbine

(yō-hĭm′bēn′)
n.
An alkaloid, C21H26N2O3, that is derived from the bark of a tree, Pausinystalia johimbe, and is an alpha-blocker drug used in the form of its hydrochloride as a mydriatic, a treatment for erectile dysfunction, and formerly as an aphrodisiac.

yohimbine

Pharmacognosy
An indolamine alkaloid obtained from the bark of the West African yohimbe tree (Pausinystalia yohimbe) and others (e.g., Rauwolfia serpentina). Yohimbine is used for psychogenic and organic erectile dysfunction, increasing the inflow to and/or decreasing the outflow of blood from the penis by blocking the pre- and post-synaptic alpha-2 adrenoceptors. It has been studied for treating orthostatic hypotension and ischaemia due to autonomonic dysfunction in diabetes and narcotic overdose.

Toxicity
Tachcardia, hypertension, insomnia, nausea, palpitations, tremors, vomiting.

yohimbine

Pharmacognosy An alkaloid used to treat erectile dysfunction, which is chemically similar to reserpine; it may be of use for orthostatic hypotension and ischemic vascular disease caused by autonomonic dysfunction in DM, narcotic overdose, possibly acting to ↑ dopamine release, and for psychogenic and organic impotence, possibly ↑ inflow to and/or ↓ outflow of blood from the penis, with ↑ erection without ↑ sexual desire

yo·him·bine

(yō-him'bēn)
An alkaloid, the active principle of yohimbé, the bark of Corynanthe yohimbi; produces a competitive blockade, of limited duration, of adrenergic α-receptors; has also been used for its alleged aphrodisiac properties.

yo·him·bine

(yō-him'bēn)
An alkaloid, active principle of yohimbé, bark of Corynanthe yohimbi; it produces a competitive blockade, of limited duration, of adrenergic α-receptors; has also been used for its alleged aphrodisiac properties.

yohimbine (yōhim´bēn´),

n an alkaloid, the active principle comes from the bark of
Corynanthe johimbe. It produces a competitive blockage of limited duration of α-adrenergic receptors. It has also been used for its alleged aphrodisiac properties.

yohimbine

an α2 adrenoceptor antagonist used to reverse sedation produced by α2 adrenoceptor agonists such as xylazine.

yohimbine challenge test
used as a test for cataplexy in dogs; after administration, there is a marked reduction in the number and severity of clinical signs.
References in periodicals archive ?
Moreover, the analysis of drug response genomewide microarray data reveals that high doses of yohimbine can activate BAG6 in stage 1 bladder cancer, while high doses of chlorpromazine can activate HSPA5 and JUN in stage 4 bladder cancer.
Consumption of Yohimbine may cause unwanted side effects, the health services said.
Hence, many of the former customers of the drugs Alprostadil or Yohimbine immediately started taking Viagra.
Yohimbine can bind to the same receptors, blocking the effects of adrenaline and allowing more insulin to be released.
Yohimbine stress potentiates conditioned cue-induced reinstatement of heroin-seeking in rats.
The older version of the Grenade Fat Burner pills also contained yohimbine, another herbal stimulant that can cause side effects, such as rapid heart rate, high blood pressure, headaches and has even been linked to seizures and kidney failure.
Assessment of alpha-2 adrenergic autoreceptor function in humans: Effects of oral yohimbine.
granisetron, amantadine, mirtazapine, yohimbine, ephedrine, or ginkgo biloba in women RCTs: randomized controlled trials; SSRI: selective serotonin reuptake inhibitor Source: Reference 7.
Evaluation of selected parameters of rat liver and kidney function following repeated administration of yohimbine.
There's also meant to be a powerful "love potion" scent made from natural perfumes and alleged aphrodisiacs phenethyleamine and yohimbine, which guides visitors to what is described as a wedding grotto.
Some of the newer beverages are throwing in powerful herbal compounds such as yohimbine hydrochloride and evodiamine (EVO).