Adult male Crl:NIH-Foxnl[mu] nude rats (strain code 316) and BALB/c nude mice (strain code 194) 8-10 weeks of age were obtained from Charles River Laboratories (Wilmington, MA) and used as hosts for xenotransplant
It is therefore obligatory to look into the current research knowledge about xenotransplants
(organs from one species to another, for example animal to human) in more detail.
CollapAn L" is a xenotransplant
consisting of a synthetic bone-salt (hydroxyapatite) and scleral collagen available in patches, granules and gels.
require life-long surveillance of xenotransplant
recipients because of
Although he believes the possibility of an unknown virus that jumps species or a new recombinant virus that emerges in xenotransplant
patients is remote, he also urges extreme caution in eventual human trials, with mandatory lifelong monitoring of recipients and their intimate contacts.
The risk of inadvertent infection does not end with the xenotransplant
recipient, but extends as well to the risk of subsequent secondary transmission of infection by the recipient to the wider population.
The text offers a technical overview of the state of xenotransplant
research, which is still in early stages, and a detailed analysis of potential ethical issues.
Inherent in the xenotransplant
process is the maintenance of patient confidentiality, which makes it difficult to adequately monitor recipients.
and xenograft are used interchangeably.
Q: Do you think that use of xenotransplant
tissues, such as islet cells from pigs, might occur soon?
It will take only one xenotransplant
to start an epidemic.
This conference called for the creation of a national Xenotransplantation Advisory Committee--comprised of scientists, physicians, ethicists, lawyers, and public representatives--to review public safety issues, using guidelines established by the transplant community for monitoring of infectious complications following clinical xenotransplant