xenodiagnosis


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xenodiagnosis

 [zen″o-di″ag-no´sis]
1. diagnosis by means of finding, in the feces of clean laboratory-bred bugs fed on the patient, the infective forms of the organism causing the disease; used in the early stages of Chagas' disease.
2. diagnosis of trichinosis by means of feeding laboratory-bred rats or mice on meat suspected of being infected with Trichinella, and then examining the animals for the parasite. adj., adj xenodiagnos´tic.

xen·o·di·ag·no·sis

(zen'ō-dī'ag-nō'sis),
1. A method of diagnosing acute or early Trypanosoma cruzi infection (Chagas disease) in humans. Infection-free (laboratory-reared) triatomine bugs are fed on the patient's tissue and the trypanosome is identified by microscopic examination of the bug's intestinal contents after an incubation period.
2. A similar method of biologic diagnosis based on experimental exposure of a parasite-free normal host capable of allowing the organism in question to multiply, enabling it to be more easily and reliably detected.

xenodiagnosis

(zĕn′ə-dī′əg-nō′sĭs, zē′nə-)
n. pl. xenodiagno·ses (-sēz)
Diagnosis of an infectious disease at an early stage by exposing a presumably infected individual or tissue to a clean, laboratory-bred mosquito, tick, or other vector and then examining the vector for the presence of the infective microorganism.

xen′o·di·ag·nos′tic (-nŏs′tĭk) adj.

xen·o·di·ag·no·sis

(zen'ō-dī'ăg-nō'sis)
1. A method of diagnosing acute or early Trypanosoma cruzi infection (Chagas disease) in humans. Infection-free triatomine insects are permitted to feed on the person thought to be infected, and the trypanosome is identified by microscopic examination of the intestinal contents of the insect after a suitable incubation period.
2. A similar method of biologic diagnosis based on experimental exposure of a parasite-free normal host capable of allowing the organism in question to multiply, enabling it to be more easily and reliably detected.
References in periodicals archive ?
Xenodiagnosis was conducted by using 20 stage 3 nymphs of Rhodnius robustus and R.
The identification of Trypanosoma species was performed by xenodiagnosis of positive mice with 12 reared III instar nymphs of R.
To evaluate the sensitivity and specificity of the AgA-ELISA we used 60 sera from healthy individuals (with negative results in three different serological tests) and 70 previously positive sera from chagasic patients (positive by xenodiagnosis).
We added two indirect parasitological methods--artificial xenodiagnosis and blood culture for T.
Trypanosoma cruzi parasitemia observed in immunocompromised patients: the importance of the artificial xenodiagnosis. Revista do Instituto de Medicina Tropical de Sao Paulo, v.43, n.2, p.113-115, 2001.
bacteria binary fission capnophil coliform endotoxin enterotoxin eukaryote exotoxin facultative microaerophil nomenclature obligate prokaryote taxonomy thermophil xenodiagnosis OVERVIEW
Xenodiagnosis is a parasitologic diagnostic method that may be used to diagnose Chagas disease (Barrett et al., 2003).
During the acute phase of infection, diagnosis involves detection of circulating organisms by microscopic examination of a fresh blood specimen or stained blood smear, hemoculture, or xenodiagnosis (1).
Parasites detected at 3 mo when acute Chagas disease diagnosed in newborn and concomitantly found by direct methods in mothers' milk Medina-Lopes Acute Wk 5 of maternal acute infection and Macedo, (before delivery): direct 1983 (28) examination of colostrum: negative; intraperitoneal inoculation of mice with colostrum and xenodiagnosis: positive.
Detection of Trypanosoma cruzi in blood specimens of chronic chagasic patients by Polymerase Reaction Chain amplification of kinetoplast minicircle DNA: Comparison with serology and xenodiagnosis. J Clin Microbiol 1993, 31:2421-2426.
Injection of blood from infected humans into laboratory animals followed by examination of the laboratory animal's blood sometimes is useful in diagnosing this disease (xenodiagnosis).