xanthomatosis


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Related to xanthomatosis: cerebrotendinous xanthomatosis

xanthomatosis

 [zan″tho-mah-to´sis]
an accumulation of excess lipids in the body due to disturbance of lipid metabolism and marked by the formation of foam cells in skin lesions called xanthomas.
xanthomatosis bul´bi fatty degeneration of the cornea due to disorder of lipid metabolism, marked by the presence of xanthomas.
chronic idiopathic xanthomatosis Hand-Schüller-Christian disease.

xan·tho·ma·to·sis

(zan'thō-mă-tō'sis),
Widespread xanthomas, especially on the elbows and knees, that sometimes affect mucous membranes and are sometimes associated with metabolic disturbances.

xanthomatosis

/xan·tho·ma·to·sis/ (zan″tho-mah-to´sis) a condition marked by the presence of xanthomas.
xanthomatosis bul´bi  fatty degeneration of the cornea.

xanthomatosis

(zăn′thō-mə-tō′sĭs)
n.
A metabolic disorder characterized by excessive accumulation of lipids in the body and a resulting spread of xanthomas.

xanthomatosis

[zan′thōmətō′sis]
Etymology: Gk, xanthos + oma + osis, condition
an abnormal condition in which there are deposits of yellowish fatty material in the skin, internal organs, and reticuloendothelial system. It may be associated with hyperlipoproteinemia, paraproteinemia, lipoid storage diseases, and other disorders of adipose tissue. Also called xanthosis. See also lipemia, xanthoma, xanthoma palpebrarum.

xanthomatosis

A generalized, nonspecific ↑ in xanthomas that may occur in malignancy–eg, lymphoma, multiple myeloma, or occur in other disease–eg, familial hypercholesterolemia syndrome, Langerhans' cell histiocytosis-Hand-Schüller-Christian type, Wolman's disease

xan·tho·ma·to·sis

(zan'thō-mă-tō'sis)
Widespread xanthomas, especially on the elbows and knees, which sometimes affect mucous membranes and are sometimes associated with metabolic disturbances.
Synonym(s): lipid granulomatosis, lipoid granulomatosis, xanthoma multiplex.

xanthomatosis

A condition occurring in various, often hereditary, disorders of fat metabolism, in which cholesterol-containing fatty nodules (xanthomas) occur in different parts of the body, including the tendons, arteries, the skin, the corneas, the crystalline lenses, the internal organs and the brain. The effects depend on the site of the deposits and may include mental deficit. Treatment with CHENODEOXYCHOLIC ACID, to inhibit synthesis of bile acids, may help.

xan·tho·ma·to·sis

(zan'thō-mă-tō'sis)
Widespread xanthomas, especially on elbows and knees, which sometimes affect mucous membranes and may be associated with metabolic disturbances.

xanthomatosis

an accumulation of excess lipids in the body due to disturbance of lipid metabolism and marked by the formation of foam cells and Touton giant cells in skin lesions. Occurs in association with diabetes mellitus in the dog and is common in humans and chickens. See also xanthoma.
References in periodicals archive ?
Xanthomas and xanthomatosis are most commonly recognized as disorders of the avian integument, with lesions often overlying deeper tissue masses.
Dietary cholesterol-induced xanthomatosis in atherosclerosis-susceptible Japanese quail (Coturnix japonica).
Cerebrotendinous xanthomatosis treatment includes chenodeoxycholic acid and HMG-CoA-reductase inhibitors.
Psychiatric disorders in patients with cerebrotendinous xanthomatosis.
Hyperlipidemia xanthomatosis with associated osseous granuloma.
High-throughput urine screening for SmithLemli-Opitz syndrome and cerebrotendinous xanthomatosis using negative electrospray tandem mass spectrometry.
We show the clinical usefulness of the technique by successfully applying it to 4 inherited disorders in lipid metabolism: SLOS, cerebrotendinous xanthomatosis (CTX), sitosterolemia, and Refsum disease.
FH is characterized by a selective increase of plasma LDL-cholesterol, giving rise to tendon and skin xanthomatosis and to premature coronary heart disease (1,2).
Identification of new mutations in sterol 27hydroxylase gene in Japanese patients with cerebrotendinous xanthomatosis (CTX).