xanthomatosis


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Related to xanthomatosis: cerebrotendinous xanthomatosis

xanthomatosis

 [zan″tho-mah-to´sis]
an accumulation of excess lipids in the body due to disturbance of lipid metabolism and marked by the formation of foam cells in skin lesions called xanthomas.
xanthomatosis bul´bi fatty degeneration of the cornea due to disorder of lipid metabolism, marked by the presence of xanthomas.
chronic idiopathic xanthomatosis Hand-Schüller-Christian disease.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

xan·tho·ma·to·sis

(zan'thō-mă-tō'sis),
Widespread xanthomas, especially on the elbows and knees, that sometimes affect mucous membranes and are sometimes associated with metabolic disturbances.
Farlex Partner Medical Dictionary © Farlex 2012

xanthomatosis

(zăn′thō-mə-tō′sĭs)
n.
A metabolic disorder characterized by excessive accumulation of lipids in the body and a resulting spread of xanthomas.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

xanthomatosis

A generalized, nonspecific ↑ in xanthomas that may occur in malignancy–eg, lymphoma, multiple myeloma, or occur in other disease–eg, familial hypercholesterolemia syndrome, Langerhans' cell histiocytosis-Hand-Schüller-Christian type, Wolman's disease
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

xan·tho·ma·to·sis

(zan'thō-mă-tō'sis)
Widespread xanthomas, especially on the elbows and knees, which sometimes affect mucous membranes and are sometimes associated with metabolic disturbances.
Synonym(s): lipid granulomatosis, lipoid granulomatosis, xanthoma multiplex.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

xanthomatosis

A condition occurring in various, often hereditary, disorders of fat metabolism, in which cholesterol-containing fatty nodules (xanthomas) occur in different parts of the body, including the tendons, arteries, the skin, the corneas, the crystalline lenses, the internal organs and the brain. The effects depend on the site of the deposits and may include mental deficit. Treatment with CHENODEOXYCHOLIC ACID, to inhibit synthesis of bile acids, may help.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

xan·tho·ma·to·sis

(zan'thō-mă-tō'sis)
Widespread xanthomas, especially on elbows and knees, which sometimes affect mucous membranes and may be associated with metabolic disturbances.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Cerebrotendinous xanthomatosis, a metabolic disease with different neurological signs: two case reports.
Xanthoma disseminatum: a rare normolipemic xanthomatosis. Clin Investig.
Avian xanthomatosis is relatively common in psittacine and gallinaceous birds, possibly because of high lipid diets and their more sedentary lifestyles.
DISCUSSION: Cerebrotendinous xanthomatosis is an autosomal recessive lipid storage disorder caused by mutations in CYP27A gene, located in 2q33-qter, which codes for hepatic mitochondrial sterol 27-hydroxylase, involved in the normal biosynthesis of bile acids.
The method contributes to the diagnosis of some rare genetic diseases like cerebrotendinous xanthomatosis, Niemann-Pick type C disease, and Smith-LemliOpitz-Syndrome in a single run.
Similarly severe physical signs but modest elevations in LDL are seen in cerebrotendinous xanthomatosis. This rare recessive disorder is due to a defect in bile acid synthesis (26 hydroxylase deficiency) and in addition to xanthomata that commence later in childhood, it results in cataracts and central nervous system degeneration.
-- Papular xanthoma is a distinct type of normolipernic xanthomatosis that was first described in 1980, Dr.
Involvement of the temporal bone in hyperlipidemic xanthomatosis. Otolaryngol Head Neck Surg 1983;91:100-4.
700 Washington, DC 20036-5602 (800) 872-5827 (202) 776-0406 (202) 973-7197 (TTY) (202) 776-0414 (fax) www.ucpa.org ??ucpainc@aol.com 1,2,3,4,5,6,7,8; Spanish materials, provides direct services through 158 affiliate programs CEREBR00CULORENAL DYSTROPHY See: Lowe Syndrome CEREBROSIDE LIPIDOSIS See: Gaucher Disease CEREBROTENDINOUS See: Xanthomatosis Leukodystrophy; Tay-Sachs Disease CHAGAS' DISEASE See: Autoimmune Disorders CHALASODERMIA See: Connective Tissue Disorders CHANARIN-DORFMAN SYNDROME See: Ichthyosis CHANDS ASSOCIATION See: Ectodermal Dysplasias CHARCOT-MARIE-TOOTH DISEASE See also: Ataxia; Muscular Dystrophy; Myelin Disorders Charcot-Marie-Tooth Association 601 Upland Ave.
Localized morphea, xanthomatosis and primary biliary cirrhosis.
In vitro characterization of a monoclonal IgG from a patient with planar xanthomatosis. Eur J Haematol 2008;80:495-502.
The differential diagnosis included inflammatory arthritidies (such as rheumatoid arthritis or psoriatic arthritis), gouty arthritis, amyloidosis, pigmented villonodular synovitis, and xanthomatosis. Other causes of carpal tunnel syndrome (such as congestive heart failure, myxedema, and trauma) did not match this patient's clinical and imaging findings.