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a form of pyelonephritis that results in a chronic inflammatory condition; the kidney enlarges and becomes less functional or nonfunctional; characterized histologically by the presence of lipid-laden, foamy macrophages and multiple granulomas. Can mimic neoplasms and renal tuberculosis and is a global process that affects the whole kidney.
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xanthogranulomatous pyelonephritisNephrology A malakoplakia-like kidney lesion that lacks Michaelis-Gutmann bodies, arising in an E coli or Proteus spp infection Complications Hydronephrosis, nephrolithiasis
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
xanthogranulomatous pyelonephritisAbbreviation: XGP
A relatively rare form of chronic destructive kidney infection in which a kidney, usually one obstructed by stones, becomes enlarged, necrotic, and functionless. In most cases the diseased kidney is surgically removed.
See also: pyelonephritis
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