xanthogranulomatous inflammation

xanthogranulomatous inflammation

A nonspecific term for a disparate group of conditions that share a common pathology of a wedge-shaped infiltrate of lipid-laden S-100-negative histiocytes/macrophages accompanied by mixed inflammatory cells, including lymphocytes, plasma cells, neutrophils and eosinophils, with sparing of the epidermis.

Examples
Fat necrosis, lipophages, xanthoma, xanthogranuloma, non-Langerhans cell histiocytosis, xanthogranulomatous necrobiosis, tumours (e.g., benign fibrous histiocytoma, giant cell tumour), verruciform xanthoma.

DiffDx
Tuberculosis, fungal infections.
References in periodicals archive ?
Both lesions had xanthogranulomatous inflammation with numerous foamy histiocytes and extensive fibrosis extending into the muscularis propria.
In avian medicine, the syndromes of xanthoma, xanthomatosis, and xanthogranulomatous inflammation have not been consistently defined or separated (Table 1).
The xanthogranulomatous process; xanthogranulomatous inflammation.
The predominant finding in the excised mass obtained from our patient was xanthogranulomatous inflammation, although the mass did contain small areas of residual Warthin's tumor.
The spindle cell proliferation that accompanies the xanthogranulomatous inflammation could be confused with a mesenchymal neoplasm such as a low-grade sarcoma.
Xanthogranulomatous inflammation of the sigmoid colon: A case report.
Malacoplakia is an unusual yet well-documented form of chronic xanthogranulomatous inflammation.
Xanthogranulomatous inflammation is a form of chronic inflammation that is destructive to the normal tissue of affected organs.
The pathogenesis of xanthogranulomatous inflammation remains unclear.
Walther et al[28] have suggested that malakoplakia and xanthogranulomatous inflammation may have a common pathogenesis.
12,13,20,22] Bacteria have also been associated with xanthogranulomatous inflammation in other organs[5,6,7,10,14] Escherichia coli was cultured from ovarian abscess fluid in the present case.
Histologic findings were also characteristic of xanthogranulomatous inflammation.