xanthine oxidase

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xan·thine ox·i·dase

a flavoprotein containing molybdenum; an oxidoreductase catalyzing the reaction of xanthine, O2, and H2O to produce urate and superoxide. Also oxidizes hypoxanthine, some other purines and pterins, and aldehydes. A lower rate of oxidation is observed in patients with molybdenum cofactor deficiency.
Farlex Partner Medical Dictionary © Farlex 2012

xan·thine ox·i·dase

(zanthēn oksi-dās)
Flavoprotein containing molybdenum; also oxidizes hypoxanthine, some other purines and pterins, and aldehydes.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


Franz, Austrian scientist, 1853-1920.
Schardinger dextrins - the result of action of Bacillus macerans on starch.
Schardinger enzyme - a flavoprotein containing molybdenum. Synonym(s): xanthine oxidase
Schardinger reaction - an example of oxidation in the absence of O2 with an organic hydrogen acceptor.
Medical Eponyms © Farlex 2012
References in periodicals archive ?
Xanthine Oxidase Inhibitor, Allopurinol, Prevented Oxidative Stress, Fibrosis, and Myocardial Damage in Isoproterenol Induced Aged Rats.
Guidelines also recommend adding a uricosuric agent (lesinurad or probenecid) or switching to a uricosuric agent (probenecid) if the sUA target level cannot be reached by an appropriate dosage of a xanthine oxidase inhibitor or when a xanthine oxidase inhibitor is not tolerated.
Da Silva et al., "9-Benzoyl 9-deazaguanines as potent xanthine oxidase inhibitors," Bioorganic and Medicinal Chemistry, vol.
Canas, "The role of xanthine oxidase and the effects of antioxidants in ischemia reperfusion cell injury," Acta Physiologica, Pharmacologica et Therapeutica Latinoamericana, vol.
* A tannin-rich fruit extract appears to inhibit xanthine oxidase, an enzyme involved in uric acid synthesis.
The absence of C-2-C-3 double bond as well as ketonic group at C-4 in ring C reduced the xanthine oxidase, [alpha]-glucosidase, and DPP-4 inhibitory activities.
Xanthine oxidase activity was measured in serum, which was diluted 1: 1 with cytochrome c (100 [micro]M) in PBS containing either hypoxanthine (1mM) or allopurinol (1mM) [41].
Li, Inhibition of Xanthine oxidase, Lipoxygenase and Cyclooxy-genase by the extracts from the medicinal plants of Selaginella genus (Doctoral Thesis of Chinese traditional medicine) [Ph.D.
This randomized, double-blind, placebo-controlled study evaluated the effects of Ayuric, a natural xanthine oxidase inhibitor, and the prescription gout medication febuxostat on uric acid levels in subjects with hyperuricemia.
XOR exists in two distinct functional but interconver-tible forms: xanthine oxidase (XO; xanthine- oxygen oxidoreductase; EC (, which catalyzes reactions 1 and 2, and xanthine dehydrogenase (XDH; xanthineNAD oxidoreductase; EC (1.17.1.
Folic acid, a B vitamin when taken in large doses can inhibit the production of xanthine oxidase, the enzyme whose job is to produce uric acid.
The various enzymes included in the study were lipoxygenase, xanthine oxidase, acetyl cholinesterase, butyryl cholinesterase and protease.