wrinkle
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wrin·kle
(ring'kĕl),A furrow, fold, or crease in the skin, particularly of a type seen with increasing occurrence as a result of sun exposure or, in perioral skin, cigarette smoking; associated with degeneration of dermal elastic tissue.
Farlex Partner Medical Dictionary © Farlex 2012
wrinkle
(rĭng′kl) [AS. gewrinclian, to wind]1. A crevice, furrow, or ridge in the skin.
2. To make creases or furrows, as in the skin by habitual frowning.
Medical Dictionary, © 2009 Farlex and Partners