withdrawal syndrome


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withdrawal

 [with-draw´al]
1. a pathological retreat from interpersonal contact and social involvement, as may occur in avoidant, schizoid, or schizotypal personality disorders.
2. the removal of something.
3. a substance-specific substance-induced disorder that follows the cessation of use or reduction in intake of a psychoactive substance that had been regularly used to induce a state of intoxication. Specific withdrawal syndromes include those for alcohol, amphetamines or similarly acting sympathomimetics, cocaine, nicotine, opioids, and sedatives, hypnotics, or antianxiety agents. Called also abstinence syndrome, withdrawal symptoms, and withdrawal syndrome.



The usual reactions to alcohol withdrawal are anxiety, weakness, gastrointestinal symptoms, nausea and vomiting, tremor, fever, rapid heartbeat, convulsions, and delirium (see also delirium tremens). Similar effects are produced by withdrawal of barbiturates and in this case convulsions occur frequently, often followed by psychosis with hallucinations. Treatment of withdrawal consists of providing a substitute drug such as a mild sedative, along with treatment of the symptoms as needed. Parenteral fluids are often required.
substance withdrawal withdrawal (def. 3).
withdrawal syndrome former name for withdrawal (def. 3).
thought withdrawal the delusion that someone or something is removing thoughts from one's mind.

with·draw·al syn·drome

the development of a substance-specific syndrome that follows the cessation of, or reduction in, intake of a psychoactive substance that the person previously used regularly; for example, clinical syndrome of disorientation, perceptual disturbance, and psychomotor agitation following the cessation of chronic use of excessive quantities of alcohol is termed alcohol withdrawal syndrome. The syndrome that develops varies according to the psychoactive substance used. Common symptoms include anxiety, restlessness, irritability, insomnia, and impaired attention.
See also: abstinence syndrome, withdrawal, withdrawal symptoms.

with·draw·al syn·drome

the development of a substance-specific syndrome that follows the cessation of, or reduction in, intake of a psychoactive substance that the person previously used regularly; for example, clinical syndrome of disorientation, perceptual disturbance, and psychomotor agitation following the cessation of chronic use of excessive quantities of alcohol is termed alcohol withdrawal syndrome. The syndrome that develops varies according to the psychoactive substance used. Common symptoms include anxiety, restlessness, irritability, insomnia, and impaired attention.
See also: abstinence syndrome, withdrawal, withdrawal symptoms.

withdrawal syndrome

Cardiology A constellation of findings, including angina and acute MI, that may follow abrupt cessation of β-blockers in Pts with HTN Psychology See Withdrawal Substance abuse A constellation of Sx that follow the abrupt cessation of psychoactive agents, which is largely a function of the withdrawn agent.

with·draw·al syn·drome

(with-draw'ăl sin'drōm)
A substance-specific syndrome that follows the cessation of, or reduction in, intake of a psychoactive substance previously used regularly. The syndrome that develops varies according to the psychoactive substance used. Common symptoms include anxiety, restlessness, irritability, insomnia, and impaired attention.

withdrawal syndrome

The complex of symptoms experienced on withdrawal of a drug on which a person is physically dependent. Symptoms of heroin withdrawal include craving for the drug, restlessness, depression, running nose, yawning, pain in the abdomen, vomiting, diarrhoea, loss of appetite, sweating and gooseflesh (‘cold turkey’). Those caused by withdrawal of other narcotic drugs are similar but less intense. See also DETOXIFICATION UNDER ANAESTHESIA.

with·draw·al syn·drome

(with-draw'ăl sin'drōm)
Development of a substance-specific syndrome that follows cessation of, or reduction in, intake of a psychoactive substance that the person previously used regularly; e.g., clinical syndrome of disorientation, perceptual disturbance, and psychomotor agitation following cessation of chronic use of excessive quantities of alcohol is termed alcohol withdrawal syndrome.
References in periodicals archive ?
Our study also shows that central administration of ramelteon at 25, 50 and 100 [micro]g/5 [micro]l can mitigate the total morphine withdrawal syndrome. Lastly, systemic administration of ramelteon at 20 and 40 mg/kg and central administration of ramelteon at 50 and 100 [micro]g significantly attenuates blood cortisol levels during withdrawal episodes.
Staff had extensive experience with withdrawal syndrome, with 79% reporting caring for more than five patients undergoing withdrawal, and 44% reporting caring for more than 25 patients undergoing withdrawal syndrome.
Patients with alcohol withdrawal syndrome are usually apprehensive or fearful.
In January 2011, a diagnosis of rabies was considered in a Wisconsin man with encephalopathy who was hospitalized for treatment of alcohol withdrawal syndrome. He died nearly 2 weeks later of rabies.
Many experts concur that stopping treatment late in pregnancy is not necessarily the ideal approach and that women with depression responsive to SSRIs or SNRIs should be properly treated, especially since the neonatal withdrawal syndrome is self-limited.
Treatment with benzodiazepines did not help the syndrome and may even have exacerbated it, although the resolution of the syndrome with reduction in benzodiazepines may have been a coincidence related to the natural course of this kind of withdrawal syndrome. The one reported case of a GHB withdrawal seizure describes a patient who had violent agitation following treatment with IV diazepam, biting staff while in the postictal phase (Chew & Fernando 2004).
A double-blind placebo-controlled trial of magnesium sulfate in the ethanol withdrawal syndrome. Alcohol Clin Exp Res 1984; 8:542-545.
Research findings show that when subjects smoke two joints daily for 28 days and then stop, they have a withdrawal syndrome marked by irritability, restlessness, weight loss, insomnia, and tremor that begins 10 hours after their last joint and lasts 4-5 days, with maximum intensity at 28 hours.
"Addiction is often, but not always, accompanied by physical dependence, withdrawal syndrome, and tolerance.
Some patients who discontinue an SSRI (particularly paroxetine) experience a withdrawal syndrome that is characterized by a type of vertigo that occurs in association with visual tracking and is described as visual lag.
KEY WORDS: neurobehavioral theory of AODU (AOD [alcohol or other drug] use, abuse, and dependence); brain; synapse; neuron; cell signaling; intracellular messengers; protein kinases; phosphorylation; AOD tolerance; AOD withdrawal syndrome.