windup


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Related to windup: blustery, winding down

windup

Central sensitization, neuroplasticity Anesthesiology A physiologic ↑ sensitization of excitable neurons, coupled to a ↓ threshold for peripheral afferent pain terminals; windup may be mediated by excitatory amino acid neurotransmitters and neuropeptides; NMDA receptor inhibitors prevent 'windup' and may play a central role in managing chronic pain. See NMDA receptor antagonist, Preemptive analgesia. Cf Multimodality pain control.
References in periodicals archive ?
In operation, each of the three tread windup machines now automatically deposits its rolls onto Hytrol powered roller conveyors.
Had Nomo been recovering from the landing on his windup, he never would have been able to snare the ball.
Nomo, who surprised his manager and catcher by skipping his twisting tornado windup, allowed a single by Derek Bell and a two-run homer to Jeff Bagwell in the first inning.
Inexperienced octopus throwers sometimes make the mistake of holding the tentacle tips, only to have the octopus head break off during the windup.
Photo: This windup toy of Charlie Chaplin dressed as the Li ttle Tramp is 6-1/2 inches high.
It was great to get together in the studio with the old Goffy in the Morning team again to record the Very Best of Goffy's Windups Volume 4," he tells us.
Two- or three-roll units with windups, let-offs, strip knives and stock guides.
Graeme Hawksfield, manager of the Gateshead branch, says the CD ( Fourteen of the Most Outrageous Windups ( is number six in the in-store charts and could be top at Christmas.