wheal-and-erythema reaction

wheal-and-er·y·the·ma re·ac·tion

the characteristic immediate reaction observed in an allergy skin test; within 10-15 minutes after injection of antigen (allergen), an irregular, blanched, elevated wheal appears, surrounded by an area of erythema (flare).

wheal-and-er·y·the·ma re·ac·tion

(wēl er'i-thē'mă rē-ak'shŭn)
The characteristic immediate reaction observed in the skin test; within 10-15 minutes after injection of antigen (allergen), an irregular, blanched, elevated wheal appears, surrounded by an area of erythema (flare).
Synonym(s): wheal-and-flare reaction.