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A gene on chromosome 3q21-q23 that encodes a member of the ephrin-B receptor subfamily of receptor tyrosine kinases, which “promiscuously” bind membrane-bound ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighbouring cells. EPHB1 regulates retinal axon guidance, ipsilaterally redirecting ventrotemporal retinal ganglion cells axons at the optic chiasm midline during nervous system development, a process that is thought to require repulsive interaction with EFNB2. In the adult nervous system, EPHB1 and EFNB3 regulate chemotaxis, proliferation and polarity of the hippocampus neural progenitors.

In addition to its role in axon guidance, EPHB1 also plays a key redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. It may also regulate angiogenesis and play a role in targeted cell migration by activating the MAPK/ERK cascade, and in adhesion by activating the JNK signalling cascade. EPHB1’s cognate/functional ephrin ligands include EFNB1, EFNB2 and EFNB3.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Ears–nose and throat, lungs, kidneys An acronym for the organs involved in Wegener's granulomatosis–WG; limited WG spares the kidneys and lacks signs of systemic vasculitis; generalized WG involves the kidneys and/or has signs of systemic vasculitis; disease exacerbation is best monitored by measuring titers of antineutrophil cytoplasmic antibodies by indirect immunofluorescence. See Wegener's granulomatosis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The wells on the 9-3 pad are the Company's first Wapiti wells fracked with the same completion design as utilized at Karr.
3 Norway 13 y Reindeer Norway 3-4 y Elk or wapiti Canada 6 y Elk or wapiti Canada Adult Elk or wapiti Canada 6 y White-tailed deer Canada 4 y Moose Canada Adult Sheep Italy 2.5 y Sheep Italy Adult Sheep Italy 4.5 y Sheep Experimental NA sample Sheep France NA Cattle Italy 6 y Cattle Italy 15 y Cattle France 11 y Animal or species Pathologic phenotype Moose no.
A traverse was made south of the Wapiti, between the stream and the Smoky, for the purpose of ascertaining the character of the country.
Wharton, "A comparison of lungworm faecal larval counts and trichostrongyloid faecal egg counts between red deer (Cervus elaphus) and red deer x wapiti F1 hybrids," New Zealand Veterinary Journal, vol.
Two versions of Arachni scanner as well as Wapiti and Skipfish scanners are evaluated in terms of speed, crawler coverage, detection accuracy, and extra supported features.
The scanners that we used were w3af, Nikto, wapiti, vega, ZAP and Acunetix (Acunetix was the only commercial tool available to us at the time of writing this paper).
Elk are also referred to as "wapiti," which is from the Shawnee and Cree tribal word waapiti meaning, "white rump."
As Theodore Roosevelt would later observe, "The wapiti is undoubtedly subject to queer freaks of panic stupidity or what seems like a mixture of tameness and puzzled terror ...
Habitat selection by wapiti Cervus elaphus xanthopygus in Wandashan Mountains based habitat availability.
"W is for Wapiti: An Alphabet Songbook" is a vivid alphabet songbook with an imaginative illustrated song/poem for every letter.
"Eight of the eight public school divisions wholeheartedly agreed (we should host the event)," said Willier, the First Nations, Metis, Inuit coordinator for Peace Wapiti School Division, which serves Grande Prairie and surrounding area.