von Willebrand


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Related to von Willebrand: Von Willebrand factor

von Wil·le·brand

(fŏn vil-le-brahnt'),
E.A., Finnish internist, 1870-1949. See: von Willebrand disease.
References in periodicals archive ?
Relationship between ABO blood group and von willebrand factor levels: From biology to clinical implications.
Hajage et al., "ADAMTS-13 and von Willebrand factor predict venous thromboembolism in patients with cancer," Journal of Thrombosis and Haemostasis, vol.
Von Willebrand syndrome is a deficiency or dysfunction of von Willebrand factor (vWF), a protein with binding sites for platelets, collagen, and factor VIII that "serves as a bridge between platelets and injury sites in vessel walls" and "protects factor VIII from rapid proteolytic degradation," Dr.
There are 1,500 registered cases of hemophilia in the Philippines and 30 of the Von Willebrand disease, said Villanueva, citing data from the Philippine Hemophilia Foundation.
Interestingly, on cultured ECs, the antiinflammatory effect of rADAMTS13 was reversed by recombinant von Willebrand factor (rVWF), suggesting that VWF mediates the effect of ADAMTS13 on vascular inflammation.
Laboratory evaluation confirmed type 1 VWD with ristocetin cofactor activity of 38%, von Willebrand antigen level of 41%, factor VIII level of 60%, and a normal von Willebrand factor multimer distribution.
Von Willebrand studies were normal (Von Willebrand factor [VWF] antigen, 112 IU/dL; ristocetin cofactor, 120 IU/dL; factor VIII [FVIII] activity, 98 IU/mL).
Acquired von Willebrand disease (AvWD) is a rare bleeding disorder [1, 2].
A 61-year-old female with a past medical history of presumed type 2 von Willebrand disease (vWD) diagnosed at age of 51 and IgM-kappa monoclonal gammopathy of undetermined significance (MGUS) diagnosed one year later presented to the hematology clinic with increasing frequency and severity of epistaxis.
Objective: To determine the frequency of Von Willebrand disease (vWD) in patients of heavy menstrual bleeding (HMB).
Low factor VIII (FVIII) [2] concentrations are associated with hemophilia A, type 2N von Willebrand disease (vWD), and combined factor V/VIII (CFV/VIII) deficiency.