PROC(redirected from vitamin K-dependent protein C)
Also found in: Dictionary, Encyclopedia.
Related to vitamin K-dependent protein C: Vitamin K Deficiency
PROCA gene on chromosome 2q13-q14 that encodes a vitamin K-dependent plasma glycoprotein, which is cleaved to its activated form by the thrombin-thrombomodulin complex. Once activated, it degrades activated coagulation factors V and VIII.
PROC mutations are linked to thrombophilia due to protein C deficiency, neonatal purpura fulminans and recurrent venous thrombosis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.