vitamin E


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Related to vitamin E: vitamin K, vitamin D

vi·ta·min E

1. Synonym(s): α-tocopherol
2. generic descriptor of tocol and tocotrienol derivatives possessing the biologic activity of α-tocopherol; contained in various oils (for example, wheat germ, cotton seed, palm, rice) and whole grain cereals where it constitutes the nonsaponifiable fraction; also contained in animal tissue (for example, liver, pancreas, heart) and lettuce; deficiency produces resorption or abortion in female rats and sterility in males. Synonym(s): antisterility factor, antisterility vitamin, fertility vitamin

vitamin E

n.
Any of several fat-soluble vitamins consisting of tocopherols, especially alpha-tocopherol, that are found chiefly in vegetable oils, nuts and seeds, wheat germ, leafy green vegetables, and milk and act as antioxidants in the body.

vitamin E

any or all of the group of fat-soluble vitamins that consist of the tocopherols and are essential for normal reproduction, muscle development, resistance of erythrocytes to hemolysis, and various other biochemical functions. It is a fat-soluble antioxidant and acts in maintaining the stability of polyunsaturated fatty acids and other fatlike substances, including vitamin A and hormones of the pituitary, adrenal, and sex glands. Deficiency is rare and may take from months to years to occur but results in muscle degeneration, vascular system abnormalities, megaloblastic anemia, hemolytic anemia, infertility, creatinuria, and liver and kidney damage and is associated with the aging process. The richest dietary sources are wheat germ; soybean, cotton seed, peanut, and corn oils; margarine; whole raw seeds and nuts; soybeans; eggs; butter; liver; sweet potatoes; and the leaves of many vegetables, such as turnip greens. It is stored in the body for long periods of time so that any deficiency is rare. It is considered nontoxic except in hypertensive patients and those with chronic rheumatic heart disease. Alpha-tocopherol is the most physiologically active form of the group. Toxicity is also rare. Also called alpha-tocopherol, tocopherol.

vitamin E

A family of eight fat-soluble antioxidant tocopherols and tocotrienols, which are found in soybeans, nuts, wheat germ and sunflower and other oils. While vitamin E deficiency is associated with a number of neurologic and immune related disorders, vitamin E supplementation does not appear to have a positive effect on health: it does not improve control of serum glucose in diabetics; it does not alter the course of age related macular degeneration; and it may increase the risk of osteoporosis and slightly increase mortality.

Biological functions of vitamin E
•  Antioxidant (peroxyl radical scavenger);
• Acts on protein kinase C, preventing the overgrowth of smooth muscle in the embryo;
•  Downregulates scavenger receptor CD36; modulates expression of connective tissue growth factor;
• Prevents oxidation of polyunsaturated fats;
• Roles in neurologic and immune activity and platelet inhibition are ongoing.

vi·ta·min E

(vī'tă-min)
Generic descriptor of tocol and tocotrienol derivatives possessing the biologic activity of α-tocopherol; contained in various oils (wheat germ, cottonseed, palm, rice) and whole grain cereals, where it constitutes the nonsaponifiable fraction, also in animal tissue (liver, pancreas, heart) and leafy vegetables; deficiency produces resorption or abortion in female rats and sterility in males.

vitamin E

or

tocopherol

a fat-soluble molecule found in many plants, such as wheatgerm oil, green leafy vegetables, egg yolk, milk and meat. The vitamin is known as an antioxidant, permitting the oxidation of, for example, unsaturated fatty acids and Vitamin A in the body. A deficiency can result in sterility.

vitamin E

alpha-tocopherol; see tocopherol

vitamin E,

n a fat-soluble vitamin found in nuts, vegetable oils, seeds, and whole grains. Has been used to remedy deficiencies and for immunomodulatory effects; to treat cataracts, cardiac autonomic neuropathy, dementia, diabetic neuropathy, painful menstruation, preeclampsia (with vitamin C supplementation), rheumatism, and type-2 diabetes. Caution for patients taking hypoglycemic medications, supplements with anticoagulant or antiplatelet effects, such as garlic, gingko, or policosanol supplements, and those undergoing chemotherapy. Caution is advised for children and pregnant or lactating women, for whom the recommended daily intake is 15 mg with a maximum daily dose of 1000 mg. Also called
alpha-tocopherol, D-tocopherol, DL-tocopherol, DL-alpha-tocopherol, tocopheryl suc-cinate, tocopheryl acetate, D-alpha-tocopherol, D-delta-tocopherol, D-beta-tocopherol, D-gamma-tocopherol, or
mixed tocopherols.

vi·ta·min E

(vī'tă-min)
1. Synonym(s): alpha-tocopherol.
2. Generic descriptor of tocol and tocotrienol derivatives possessing the biologic activity of α-tocopherol; contained in various oils (e.g., wheat germ, cotton seed, palm, rice) and whole grain cereals where it constitutes the nonsaponifiable fraction.

vitamin E

α-tocopherol, one of the three tocopherols found in wheat germ. Acts as an antioxidant in the prevention of enzootic muscle dystrophy, mulberry heart disease, hepatosis dietetica and exudative diathesis and yellow fat disease, and deficiency of the vitamin is a major cause of these diseases.

vitamin E E-responsive dermatosis
goats on selenium-deficient diets develop alopecia and seborrhea which responds to vitamin E supplementation; similar skin changes occurred in calves fed a milk substitute deficient in vitamin E.

Patient discussion about vitamin E

Q. my Dr. said to take no more than 400 iu of Vit. E. But I noticed my multiple also has 200 IU. Is this bad? I have been taking 400 units to combat Peyronies. I noticed today that my Centrum Silver also contains Vitamin E. I know taking over 400 units can be toxic, so now which way do I go from here. Thanks for any info.

A. in general, an over dose is not a very smart thing to do also in vitamins. and taking to consideration that you may have a diverse amount of vitamin E in your diet..well..you may take too much. but i have to be honest with you- i'm not a Doctor. and the one i would ask in that matter is my Doctor. all you need to do is phone him.

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References in periodicals archive ?
This is the first demonstration of a unique mechanism of how vitamin E can have some benefit in terms of cancer prevention and treatment," said lead author Ching-Shih Chen, professor of medicinal chemistry and pharmacognosy at The Ohio State University and an investigator in Ohio State's Comprehensive Cancer Center.
Fortunately, scientists have found that the gamma tocotrienol form of vitamin E may regulate certain gene signals in the skin that help prevent the damage typically seen after UVB exposure.
The 35,533 men at 427 sites were randomly assigned to oral selenium (200 meg/day) plus placebo, vitamin E (400 IU/day) plus placebo, both active agents, or two placebos, and were followed for a median of 5.
The incidence of prostate cancer rose significantly only in the vitamin E group.
Experimental rations were including; Group 1: supplementation 2% of semi-refined sunflower oil with 75 mg Vitamin E, Group 2: supplementation 2% of semi-refined sunflower oil with 150 mg Vitamin E, Group 3: supplementation 4% of semi-refined sunflower oil with 75 mg Vitamin E, Group 4: supplementation 4% of semi-refined sunflower oil with 150 mg Vitamin E, Group 5: supplementation 6% of semi-refined sunflower oil with 75 mg Vitamin E, and Group 6: supplementation 2% of semi-refined sunflower oil with 150 mg Vitamin E [table1].
Royal Saunders and co-investigators (1987, Ohio) studied the effects on lipid peroxidation of treating experimentally injured cats with a combination of vitamin E and another antioxidant, selenium.
If vitamin E does help prevent or slow cognitive decline, it's unclear exactly how it works or if supplements make a difference.
Vitamin E increases such metabolic efficiency, but excessive use can place the patient over the edge in energy output.
Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy.
Birds treated with vitamin E also have lymphocytes labeled CD-8 that kill infected cells and help eliminate foodborne pathogens.
Other studies suggest that vitamin E might protect the prostate, but the ATBC, says Albanes, "is the linchpin for testing it in the upcoming SELECT trial.
After statistical adjustment for coronary risk factors, people who had been taking at least 100 IU of vitamin E per day for at least 2 years exhibited a lower risk for coronary heart disease, compared with those who did not take the supplements.