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, virological (vī″rŏ-loj′ik) (vī″rŏ-loj′i-kăl)
Pert. to virology.
virologically (vī″rŏ-loj′i-k(ă-)lē)
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
PCR was done to assess the treatment response at four weeks of treatment (Early Virological Response or EVR), at end of 12 or 24 weeks treatment (End Treatment Response or ETR).
This retrospective study compared biochemical, virological, serological, and histopathological results in CHB patients receiving long-term treatment with lamividune, entecavir, or tenofovir.
Rapid virological response (RVR) is defined as undetectable HCV RNA using a sensitive PCR assay at week 4 of therapy, and early virological response (EVR) is defined as undetectable HCV RNA at week 12 of therapy [28, 29].
When patients were evaluated in terms of the virological responses, it was found that the patients in INI group had a significant advantage over the other groups in the first 3 months.
Polymerase chain reaction was done at the completion of 24 and 48 weeks to assess the end treatment and sustained virological response, respectively.
One reason for the increased risk of virological failure and drug resistance in children is poor palatability of paediatric drugs.
In the study ETV-901, long-term treatment with ETV achieved durable and increasing viral suppression, with undetectable HBV DNA (<300 copies/ml) being achieved in 94% of hepatitis B e antigen (HBeAg) positive patients after over 5 years of therapy and in 95% of HBeAg negative patients after over 3 years of therapy.[sup][8] Results also suggested that ETV was well tolerated[sup][9] and the viral resistance rate was very low (1.2%) following up to 6 years of treatment.[sup][10] Despite its efficacy, about 10–20% of patients treated with ETV showed a partial virological response (PVR).[sup][11],[12] These results have clearly demonstrated the efficacy of ETV in the controlled environment of randomized clinical studies.
Although the success rates of ART are considered high, other factors may be associated with the occurrence of virological failure.
PCR was done at the completion of 4 week to check for rapid virological response (RVR).
Therefore, this study aimed to investigate the influence of Treg cells at baseline and virus genotype on early virological response and drug resistance to nucleoside drugs.
A SVR was defined as HCV-RNA negativity determining by the Roche Amplicor[TM] HCV test (the lower limit of detection was 15 IU/mL) for more than 6 months after therapy, and any other outcome was considered as nonsustained virological responses (non-SVR).