virologic failure


Also found in: Acronyms.

virologic failure

Antiretroviral therapy failure, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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A 2016 meta-analysis of 43 studies involving 27,905 people in more than 26 countries conflates many of these findings into pooled odds ratios linking suboptimal adherence to virologic failure. (23) While 15 studies took place in North America, 14 occurred in sub-Saharan Africa, 6 in Europe or Australia, 5 in Asia, and 3 in several countries.
How much has adherence changed with newer antiretroviral regimens?
Virologic failure rates were estimated for patients within categorized levels of adherence and logistic regression was used to estimate the overall relationship between virologic failure and varying levels of adherence.
Evaluating Adherence to Antiretroviral Therapy Using Pharmacy Refill Records in a Rural Treatment Site in South Africa
Comparison of Three Different FDA-Approved Plasma HIV-1 RNA Assay Platforms Confirms the Virologic Failure Endpoint of 200 Copies per Milliliter Despite Improved Assay Sensitivity.
An overview of HIV and HCV viral load monitoring
The researchers counted how many people had a virologic failure in 1997-1998, 1999-2000, 2001-2002, 20032004, 2005-2006, 2007-2008, and 2009-2011.
Antiretroviral failure rate falls from over 60% to under 10% in France
Characterization of virologic failure patients on darunavir/ritonavir in treatment-experienced patients.
Nine-year follow-up of HIV-infected Romanian children and adolescents receiving lopinavir/ritonavir-containing highly active antiretroviral therapy
Virologic failure was more common among patients who had HCV genotype-la infection than among those who had HCV genotype-1b infection.
New therapies promise a better outcome in hepatitis C
Occasionally, transient low-level viremia (ie, a viral blip) is detected by viral load assays, often causing anxiety on the part of patients and clinicians about pending virologic failure or the emergence of drug resistance The occurrence of viral blips may lead clinicians to order costly and unnecessary tests and alter medication regimens of otherwise well-controlled patients.
Blips and its clinical relevance in HIV patients on treatment
When they excluded participants who discontinued the study for reasons other than virologic failure, the response rates were similar in women and men (73.0 percent vs.
No gender-based difference in HIV treatment response
In a study with patients receiving treatment at Costa Rica's Social Security System (Caja Costarricense de Seguro Social, CCSS) where more than 90% of Costa Rica's HIV patients needing treatment receive it, it was determined that virologic failure (VF) in ART was due to HIV-resistant mutants, and the appearance of these mutants was related to lack of adherence to ART or high viral load at the initiation of treatment (12).
Variabilidad de secuencias genomicas parciales del VIH-1 en pacientes costarricenses: analisis con diferentes herramientas bioinformaticas
Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults.
Changing antiretroviral therapy in children
This compared with only one of the five patients in the lopinavir/ritonavir group who experienced virologic failure. Dr.
Efavirenz may have edge for advanced HIV
Those in the nevirapine group who began nervirapine-based antiretroviral treatment within six months of childbirth were at substantial risk of virologic failure (41.7% of the 60 women) compared to those in the placebo group (0 cases).
Nevirapine safe for HIV positive women for PMTCT: Zambia and Botswana studies

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