The majority of these cases will have some form of virilizing
congenital adrenal hyperplasia like classic or nonclassic 210HD.
Sertoli-stromal tumors, also known as Leydig cell tumors, are rare, androgen-secreting, virilizing
tumors in young women.
Selective estrogen receptor modulators (SERMs) and selective androgen receptor modulators (SARMs) are two classes of drugs under development for a variety of diseases due to their high specificity for ER or AR, selective anabolic activity, lack of virilizing
side effect, and ability to extend estrogen or androgen therapy .
Furthermore in obligate heterozygotes, patients for the simple virilizing
form of CAH, aldosterone secretion was found to be reduced following ACTH stimulation, suggesting an impairment of the zona glomerulosa in addition to zona fasciculata .
alteration is induced by the organotin compound called TBT (tributyltin), used as a biocide in antifouling paints and other products (Castro et al., 2012).
In humans, increased blood pressure, or even hypertension has been linked to high levels of circulating androgens, induced either by various endocrinological diseases [polycystic ovary syndrome (PCOS), adrenogenital syndrome, virilizing
gonadal tumors, enzyme defects, medication induced hyperandrogenism] (18,19), or by AAS abuse in athletes or amateur bodybuilders (1,2).
Selected Disorders of Sexual Differentiation Disorders of Sexual Differentiation Disorder Description Genital Appearance Conditions Associated with Prenatal (Postnatal) Virilization of 46,XX Individuals * 46,XX with Endocrine disorder Female (normal congenital adrenal where the adrenal ovaries and hyperplasia (most glands produce uterus) with common cause 21- extremely high genital hydroxylase levels of masculinzation deficiency) virilizing
ranging from mild hormones inutero.
A case study of virilizing
adrenal tumor in an adolescent female elite tennis player-insight into the use of anabolic steroids in young athletes.
Based on these investigations a diagnosis of virilizing
(androgen producing) tumor of ovary was made.
The observations of a longer AGD in girls with virilizing
congenital adrenal hyperplasia (Callegari et al.
Excess amounts of androgens can pose a problem, resulting in such "virilizing
effects" as acne, hirsutism (excess hair growth in "inappropriate" places, like the chin or upper lip) and thinning hair.
Damste, "Voice Changes in Adult Women Caused by Virilizing
Agents," Journal of Speech and Hearing Disorders 32, no.