In a required SEC filing three months later, Genocea still did not disclose the six-month viral shedding
results, instead stating that the results were "expected in the middle of 2017." The company expressed optimism that GEN-003 would be ready for its next round of clinical trials in the fourth quarter of 2017.
Comparative efficacy of famciclovir and valacyclovir for suppression of recurrent genital herpes and viral shedding
. Sex Transm Dis.
Comparison of viral shedding
following vaccination with inactivated and live Newcastle disease vaccines formulated with wild-type and recombinant viruses.
Patients should also be warned that because of increased genital viral shedding
during sacral recurrences, they should avoid sexual contact during outbreaks.
Heterologous protection depends on the virus strain involved; however, a reduction in clinical signs and even of oral viral shedding
in some cases may be observed (POVEY & INGERSOLL, 1975).
Primary infection is associated with larger quantities of virus shedding in the genital tract and a longer period of viral shedding
, on average 3 weeks (8).
A study was conducted in the USA to assess the impact of HIV on both HSV-2 prevalence and viral shedding
Amid the current background of inconclusive data concerning the timing of viral shedding
via the skin and body fluids and the experimental demonstration of fomite and aerosol droplet transmission of the Filoviridae, it is useful to examine the pathogenesis of Ebola virus disease (EVD).
We assessed the prevalence of latent infection and viral shedding
from 4 groups of waterfowl: naturally occurring populations of native waterfowl, captive-reared waterfowl released for shooting, introduced non-migratory waterfowl (eg, resident, wild mallards; Anas platyrhynchos), and semiwild peridomestic waterfowl (eg, park ducks) in North Carolina and Florida, USA, from 2004 to 2009.
The most significant difference between placebo and all treatment regimens was duration of viral shedding
. ASP2151 regimens were comparable to valacyclovir for viral shedding
Agenus plans to advance HerpV into a Phase 2 study in 2012 that will measure the effect of vaccination on viral shedding
in individuals infected with HSV-2.
Researchers measured viral shedding
in about 500 people with genital herpes and found that the virus was detected about 20 percent of the time, regardless of whether individuals had active herpes lesions.