Under the NIH grant, Tulane is leading a three-year study designed to develop diagnostic tools for viral hemorrhagic fevers
, some of which are caused by arenaviruses that are potential bioterrorism agents due to their high fatality rate and ease of transmission.
Funding for the company's Ebola virus, pandemic flu, and viral hemorrhagic fever
programs represents an example of broad public health and federal interest in the potential of RNAi technology to treat and prevent disease from these, and other serious and life-threatening viruses.
Nosocomial outbreak of viral hemorrhagic fever
caused by Crimean hemorrhagic fever-Congo virus in Pakistan, January 1976.
Alkhumra virus infection, a new viral hemorrhagic fever
in Saudi Arabia.
For administrative reasons, the taking of liver samples with biopsy needles and the taking of skin punch samples from the bodies of patients 2 and 3 was delayed until October 9, and by the next morning the Department of Anatomical Pathology at the University of the Witwatersrand reported observing hepatocyte necrosis and skin vasculitis compatible with viral hemorrhagic fever
(Figure 2, panel A).
However, fever together with rapid clinical deterioration and hemorrhaging in a patient returned from a suspect region should suggest viral hemorrhagic fevers
, especially if exposure to a possible reservoir could have occurred.
International SOS has been involved in the safe transport of infectious disease cases such as viral hemorrhagic fever
, tuberculosis and meningococcal disease for a number of years," says Dr Farrow.
This investigation of a case of imported viral hemorrhagic fever
in France raised several issues.
Two new diseases have been added to the list of nationally notifiable infectious diseases: viral hemorrhagic fever
and dengue fever.
Marburg hemorrhagic fever (MHF) is a rare, viral hemorrhagic fever
(VHF); the causative agent is an RNA virus in the family Filoviridae, and growing evidence demonstrates that fruit bats are the natural reservoir of Marburg virus (MARV) (1,2).
Self-contained chapters deal with each of the 4 taxonomic viral families (Flaviviridae, Arenaviridae, Bunyaviridae, and Filoviridae), which make up the category of viral hemorrhagic fever
Dengue is epidemic or endemic in virtually every country in the tropics; it is even cited in the Guinness World Records, 2002, as the world's most important viral hemorrhagic fever
and the most geographically widespread of the arthropodborne viruses.