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a vinca alkaloid used as an antineoplastic agent, primarily as a component of combination chemotherapy regimens for Hodgkin's disease, acute lymphoblastic leukemia, and non-Hodgkin's lymphomas, as well as in the treatment of other neoplastic disorders including Wilms' tumor, neuroblastoma, AIDS-associated Kaposi sarcoma, and rhabdomyosarcoma. Administered intravenously as the sulfate salt.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
An alkaloid, C46H56N4O10, originally obtained from the Madagascar periwinkle and used in its sulfate form to treat acute leukemia and a variety of other neoplasms.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
MOPPA 4-drug chemotherapy regimen for stage-III Hodgkin lymphoma.
Sterility, nausea, vomiting, immunosuppression, increased infections, myelosuppression, myelodysplasia, ANLL.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
vincristineOncovin® AIDS A dimeric vinca alkaloid used to treat KS, thrombocytopenia, leukemias, lymphomas, solid tumors and other CAs which, like vinblastine, interrupts the mitotic spindle, causing lysis of proliferating cells Adverse effects Reversible peripheral neuropathy, constipation. Cf Vinblastine.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
vincristineA vinca alkaloid anticancer drug used to treat LEUKAEMIA. The drug is on the WHO official list. A brand name is Oncovin.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005