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a group of cytotoxic alkaloids extracted from the Madagascar periwinkle (Catharanthus roseus G. Don or Vinca rosea L.) and used as antineoplastic agents; they are cell cycle specific for the M phase of cell division and disrupt the microtubules that form the spindle apparatus. The group includes vinblastine, vincristine, vindesine, and vinorelbine tartrate.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
alkaloids such as vincristine and vinblastine (antitumor agents) extracted from the periwinkle plant.
Synonym(s): Catharanthus alkaloids
Farlex Partner Medical Dictionary © Farlex 2012
vinca alkaloidsA class of cytotoxic drugs used to treat various cancers. Examples are vindesine (Eldisine), vincristine (Oncovin) and vinblastine (Velbe).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005