Most vertebrate vestibular hair cells
are topped with a bundle of stereocilia of increasing length and extended kinocilium and a bipolarity with maximum activation when deflected toward the kinocilium.
In addition to blocking calcium influx into vestibular hair cells
, nimodipine's antivertiginous effects might be attributable to its central modulation of signals secondary to peripheral vestibular irritation.
Mechanoelectrical transduction (MET) of sound and motion by the inner ear is highly dependent on the ionic composition of the fluids bathing the auditory and vestibular hair cells (Tasaki and Fernandez, 1952; Smith et al.
Mechano-electrical transduction currents in isolated vestibular hair cells of the chick.
Some (amikacin, dihydrostreptomycin, and kanamycin) are primarily and/or initially cochleotoxic, while others (streptomycin and gentamicin) destroy vestibular hair cells
before cochlear hair cells.