Rapid weight loss for morbidly obese individuals has been demonstrated with the use of very-low-calorie diets (VLCDs).
Because of the need for rapid weight reduction, a novel inpatient approach to weight loss was adopted, using a very-low-calorie diet (VLCD) and multidisciplinary team management.
Other studies have suggested that very-low-calorie diets (less than 800 kcal/day) may not be more effective than low-calorie diets (less than 1,200 kcal/day) over the long term.
A recent meta-analysis of studies that directly compared low- and very-low-calorie diets showed that in the short term (a mean of 13 weeks), patients lost 10% of initial body weight on the low-calorie diets and 16% on the very-low-calorie diets.
Low- and very-low-calorie diets are indicated for patients with BMI >35 kg/[m.sup.2]:
Among mentally healthy patients following very-low-calorie diets in clinical trials, 90% lose [greater than or equal to]10 kg and 50% lose [greater than or equal to]20 kg in the first 4 to 6 months.
-- Intensive, very-low-calorie diets
are an appropriate method of weight loss and may be superior in maintaining weight loss, compared with more modest weight-loss programs, two researchers from the University of Kentucky said at the annual meeting of the American College of Nutrition.
In general, however, 48 randomized clinical trials have shown no greater long-term weight loss with very-low-calorie diets
than with less restrictive regimens.
(5,28,29) Very-low-calorie diets
(400-500 kilocalories per day) may increase rates of weight loss initially, but at 1 year, results are similar to those of low-calorie diets (SOR: A).
Other studies have shown that 10 to 25 percent of obese people develop gallstones while on a very-low-calorie diet
. (Very-low-calorie diets
are usually defined as diets containing 800 calories a day or less.
have recently been used in weight-control programs, but even people who need to lose weight for urgent medical reasons find these regimens difficult to follow--and must remain under medical supervision.
have been shown to effect substantial but transient weight loss, and the maintenance of weight loss remains a major challenge.