5,6) Characteristics of these diseases include a high proportion of IgG4-positive plasma cells, predominantly T-lymphocytic infiltrate, storiform fibrosis, and venulitis
Microscopic features include dense periductal lymphoplasmacytic inflammation, fibrosis and obliterative venulitis
In addition, we saw involvement of the adventitial micro-vasculature, similar to the adventitial venulitis
described in a case of IgG4-related aortitis, (3) as well as involvement of several other organs.
Los rasgos del rechazo celular agudo precoz son de infiltrado linfocitario de aspecto blastico en los espacios porta y venulitis
Otra descripcion interesante por parte de Wohlwill es la presencia de venulitis
con o sin la presencia de arteritis, la cual habia sido nombrada en pocas oportunidades (12) (Figuras 2 y 3).
Histopathological investigation of AIP typically reveals dense periductal lymphoplasmacytic inflammation, periductal and parenchymal fibrosis, and obliterative venulitis
The dense, plasma cell-rich inflammation centered on the pancreatic ducts, along with venulitis
, can extend into the peripancreatic adipose tissue and create a clinical picture of a pseudotumor.
In this study, Yamashita et al (8) reported 3 patients with interstitial lymphoplasmacytic interstitial infiltrates associated with arteritis and venulitis.
Histologically, in addition to the interstitial lymphoplasmacytic infiltrate, areas of arteritis and venulitis, consisting of permeation of the subendothelium by numerous lymphocytes and plasma cells, were accompanied by narrowing or obliteration of the vascular lumina.
In brief, paraduodenal chronic pancreatitis is characterized by inflammatory, cystic, and fibrotic changes in the duodenal wall and the adjacent pancreatic tissue near the minor papilla, while autoimmune pancreatitis4 typically shows lymphoplasmacytic periductal infiltration, perilobular and sometimes diffuse cell-rich sclerosis, and venulitis
34,35) Pathologically, it is characterized by a mixed inflammatory cell infiltrate centered around the pancreatic ducts along with venulitis
The residual parenchyma showed dense sclerosis with atrophy of lobules, lymphoplasmacytic infiltrate, focal venulitis
, and perivascular and periductal fibrosis (Figure 2).