ventricular afterload

ven·tric·u·lar af·ter·load

formerly and erroneously, the arterial pressure or some other measure of the force that a ventricle must overcome while it contracts during ejection, contributed to by aortic or pulmonic artery impedance, peripheral vascular resistance, and mass and viscosity of blood; now, more rigorously expressed in terms of the wall stress, that is, the tension per unit cross-sectional area in the ventricular muscle fibers (calculated by an expansion of Laplace law using pressure, internal radius, and wall thickness) that is required to produce the intracavitary pressure required during ejection.

ven·tric·u·lar af·ter·load

(ven-trik'yū-lăr af'tĕr-lōd)
The sum total of the forces, both hemodynamic and mechanical, which the left ventricle of the heart must pump against to send oxygenated blood out into the body.
References in periodicals archive ?
Positive ventilation might influence the TAPSE by way of increasing right ventricular afterload.
Maintaining normovolaemia and preventing increase in the ventricular afterload, preload optimisation, and increased contractility of the heart.
The i-cor system, which provides Synchronized Cardiac Assist, combines the best elements of cardiac assist and augmented cardiac function associated with IABP and percutaneous ventricular assist devices but does not increase left ventricular afterload or ventricular work.
5 [micro]g, six times per day since iloprost is known to reduce residual postoperative PH, decrease right ventricular afterload, and may facilitate the early postoperative management after PEA.
The net effect of this increased muscularization and fibrosis narrowing of the vascular lumen, producing increased resistance to flow, and increasing right ventricular afterload.
As a natriuretic endogenous peptide neurohormone brain natriuretic peptide (BNP) is mainly secreted by ventricular myocytes the synthesis of which is closely related with ventricular afterload and wall tension.
LOS ANGELES -- Chronic heart failure patients who daily ate a dark chocolate bar with super-high levels of flavonol experienced favorable changes consistent with decreased vascular resistance and diminished left ventricular afterload in a randomized, double-blind, crossover pilot study.
Stiffening increases left ventricular afterload and causes left ventricular hypertrophy which in turn increases myocardial oxygen demand, thus may further increase the coronary artery disease (8).
1) An acute increase in pulmonary vascular resistance will increase right ventricular afterload and can lead to right ventricular dysfunction.
Specific therapy to augment right and left ventricular contractility and reduce right ventricular afterload by means of pulmonary vasodilatation included a loading dose (50 [micro]g/kg) followed by continuous infusion of milrinone (0.
Over time the left ventricular afterload continues to increase and in order to maintain normal systolic function the LV uses two additional mechanisms: increase preload (Frank Starling curve) and increase myocardial contractility.
Wilmer Nichols, PhD, University of Florida College of Medicine, presented data demonstrating that EECP therapy helped reverse impaired blood vessel response and elasticity to levels that patients possessed at a younger age during his presentation, "Enhanced External Counterpulsation Decreases Wave Reflection Amplitude and Reduces Left Ventricular Afterload and Systolic Stress in Patients with Refractory Angina.