ventilator-induced lung injury


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Related to ventilator-induced lung injury: atelectrauma

ventilator-induced lung injury

Volutrauma Those changes related to ventilatory support of Pts with acute respiratory failure and/or ARDS, which may exacerbate already compromised pulmonary function Management Permissive hypercapnia, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

ventilator-induced lung injury

Abbreviation: VILI
Injury to alveoli or alveolar capillaries caused by high airway pressures, excessive tidal volumes, or repeated expansion and collapse of the alveoli during mechanical ventilation. It can produce local inflammatory lung destruction and the release of inflammatory molecules throughout the systemic circulation.
See also: injury
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Zapol, "Protective and detrimental effects of sodium sulfide and hydrogen sulfide in murine ventilator-induced lung injury," Anesthesiology, vol.
Ventilator-induced lung injury. N Engl J Med 2013;369:2126-36.
Kiyono, "Ventilator-induced lung injury is associated with neutrophil infiltration, macrophage activation, and TGF-[beta]1 mRNA upregulation in rat lungs," Anesthesia & Analgesia, vol.
Hyperoxia and Ventilator-Induced Lung Injury Models
Another method includes potentially extubating patients while on ECMO, the so-called “awake ECMO” mode,[sup][17] thereby avoiding the damaging effects of ventilator-induced lung injury and the risk of ventilator-associated pneumonia.
This finding is supported by experimental evidence that mechanical ventilation with a large [V.sub.T] leads to ventilator-induced lung injury (13,14).
When used at its fullest potential, PCV may ventilate, oxygenate, and protect the patient's lungs from ventilator-induced lung injury (VILI) more efficiently than "conventional" volume ventilation.
The role of the inflammasome in ventilator-induced lung injury. Am J Respir Crit Care Med 2012;185:1141-4.
Takata, "Mechanisms of early pulmonary neutrophil sequestration in ventilator-induced lung injury in mice," American Journal of Physiology-Lung Cellular and Molecular Physiology, vol.
Background: Subsequent neutrophil (polymorphonuclear neutrophil [PMN])-predominant inflammatory response is a predominant feature of ventilator-induced lung injury (VILI), and mesenchymal stem cell (MSC) can improve mice survival model of endotoxin-induced acute lung injury, reduce lung impairs, and enhance the repair of VILI.
Huang, "Protective effects of dexmedetomidine-ketamine combination against ventilator-induced lung injury in endotoxemia rats," Journal of Surgical Research, vol.