veno-occlusive disease


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veno-occlusive disease

Liver Obliteration of the small hepatic venules, which may lead to portal HTN and cirrhosis; VOD has been linked to ingestion of bush tea. See Jamiacan vomiting sickness Lung See Pulmonary veno-occlusive disease.

veno-occlusive disease

The former name for the disease now calledsinusoidal obstruction syndrome.
See: sinusoidal obstruction syndrome.

veno-occlusive disease

A liver disorder in which the small branches of the hepatic vein within the liver become obliterated, but not by blood clotting. The condition can be caused by drinking ‘bush tea’ containing pyrrolizidine alkaloids, and in other ways. The effects are almost identical to those of the BUDD-CHIARI SYNDROME.
References in periodicals archive ?
Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients.
Etiology from most prevalent to least was as following: congenital heart diseases (27%), chronic thromboembolic pulmonary hypertension (24%), connective tissue diseases-scleroderma (14%), idiopathic PAH (8%), diastolic dysfunction (3%), pulmonary disease (3%), pulmonary veno-occlusive disease (2%), hepatopulmonary hypertension (1%), and HIV-infection associated PAH (1%).
Pharmacokinetics of busulfan: correlation with veno-occlusive disease in patients undergoing bone marrow transplantation.
Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).
Safety and efficacy of epoprostenol therapy in pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis.
He published the seminal report of hepatic veno-occlusive disease after BMT in the SAMJ.
Defibrotide is being developed for the prevention and treatment of Veno-Occlusive Disease (VOD) in stem cell transplant recipients.
However, high-dose BU is also associated with serious organ toxicity such as central nervous system toxicity or veno-occlusive disease (VOD) of the liver (5).
Jazz Pharmaceuticals distributes defibrotide in the European Union (EU) under the name Defitelio for the treatment of severe hepatic veno-occlusive disease (VOD) in patients over one month of age undergoing hematopoietic stem cell transplantation (HSCT) therapy.