This could be the reason why most of the pacients with vasospastic
angina experience a circadian change in exercise capacity (Yasue 2008).
Furthermore, the global nature of the dysvascular changes in our patient is more consistent with a generalized vasospastic
response and not a specific arterial injury.
Subsequently, she was able to perform daily activities and experienced less vasospastic
changes of the fingers on cold exposure.
attacks precipitated by exposure to cold and or emotional stimuli.
This disorder is characterized by episodic attacks, called vasospastic
attacks, that cause the blood vessels in the fingers and toes to constrict.
These increases are not associated with an increase in end organ injury or systemic acidosis and are associated with an increase in the calibre of vasospastic
To date it has not been fully established if the observed changes are a direct result of increased blood flow to the leg, or a consequence of a vasospastic
response in the feet creating a blood pooling effect in the legs.
Chronic treatment with interleukin-1 induces coronary intimal lesions and vasospastic
responses in pig in vivo.
c) If the patient suffers with vasospastic
Induction of experimental duodenal ulcers by histamine administration is mediated through both enhanced gastric acid secretion and vasospastic
action of histamine (Cho and Pfeiffer 1981).
episodes can occur in patients who have artery blockage disease and in those who do not.
angina in a patient with Fabry's disease who showed normal coronary angiographic findings.