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agent that restricts action of both neutral endopeptidase and angiotensin converting enzyme; induces vasodilatation and diuresis.
vasopeptidase inhibitorCardiology An agent–eg, omapatrilat, that inhibits neural endopeptidase and angiotensin-converting enzyme, modulating cardiac function and bp in Pts with HTN. See Isolated systolic hypertension, Omapatrilat, OPERA.
Any of a class of medications that blocks the actions of both angiotensin converting enzymes (ACE) and neural endopeptidase. Drugs from this class may be used to treat heart failure.
See also: inhibitor