vasoocclusion

vasoocclusion

/vaso·oc·clu·sion/ (-ŏ-kloo´zhun) occlusion of a blood vessel or vessels.vasoocclu´sive
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Protection of Microvascular Liver Perfusion With 5-Hydroxymethylfurfural in Sickle Cell Disease Mice Following Hypoxia-Induced Vasoocclusion
Probing vasoocclusion phenomena in sickle cell anemia via mesoscopic simulations.
Furthermore, increased adhesion of PS-expressing erythrocytes to endothelial cells contributes to vasoocclusion (Closse et al.
5 Barnard and colleagues noted that this cascade of events increased the risk of further erythrocyte sickling and would cause further vasoocclusion, and worsened shunt physiology.
However, it is not known whether the hypercoagulability is the cause or the result of vasoocclusion.
11) The rigidity of the sickled erythrocytes and increased adherence of erythrocytes to each other and to endothelium have been considered principal factors leading to acute vasoocclusion.
SCD patients suffer severe pain, vasoocclusion, anemia, organ damage, high risk of stroke and renal insufficiency.
Data from preclinical sickle cell disease models suggest that blockade of P-selectin effectively prevents the painful stoppage of circulation in small blood vessels called vasoocclusion and maintains patent blood flow," stated Dr.
Based on preclinical studies we anticipate that by intervening in the vasoocclusive process, SelG1 may reduce or eliminate pain crises and ameliorate other serious and life-threatening complications that follow vasoocclusion.
Effective therapies that target vasoocclusion are needed to address the serious complications in patients with this life-threatening disease.